STANDARD_NAME	BIOCARTA_EPO_PATHWAY
SYSTEMATIC_NAME	M12836
COLLECTION	C2:CP:BIOCARTA
MSIGDB_URL	https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/BIOCARTA_EPO_PATHWAY
NAMESPACE	HUMAN_SEQ_ACCESSION
DESCRIPTION_BRIEF	EPO Signaling Pathway
DESCRIPTION_FULL	Erythropoietin functions to increase the number of red blood cells. Thus, it has found utility as a drug for those needing to replenish erythrocytes for a number of reasons. The signaling mechanism includes multimerization of the receptor upon ligand binding, activation of MAPK cascade, and phosphorylation and activation of Stat5.
PMID	
GEOID	
AUTHORS	
CONTRIBUTOR	BioCarta
CONTRIBUTOR_ORG	BioCarta
EXACT_SOURCE	
FILTERED_BY_SIMILARITY	
EXTERNAL_NAMES_FOR_SIMILAR_TERMS	
EXTERNAL_DETAILS_URL	https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/human/h_epoPathway.gif
SOURCE_MEMBERS	AL833457,BG682876,BQ877285,NM_000121,NM_000799,NM_001040056,NM_001109891,NM_001114123,NM_001130040,NM_001130041,NM_001130442,NM_001202859,NM_001257168,NM_001895,NM_002086,NM_002228,NM_002660,NM_002746,NM_002750,NM_002755,NM_002831,NM_002880,NM_003029,NM_003152,NM_004972,NM_005229,NM_005252,NM_005343,NM_005633,NM_012448,NM_080548,NM_080549,NM_139046,NM_139047,NM_139049,NM_176795,NM_177559,NM_177560,NM_182811,NM_183001,NM_203506
GENE_SYMBOLS	SOS1,,,EPOR,EPO,MAPK3,MAPK3,ELK1,SHC1,SHC1,HRAS,SHC1,ELK1,CSNK2A1,GRB2,JUN,PLCG1,MAPK3,MAPK8,MAP2K1,PTPN6,RAF1,SHC1,STAT5A,JAK2,ELK1,FOS,HRAS,SOS1,STAT5B,PTPN6,PTPN6,MAPK8,,MAPK8,HRAS,CSNK2A1,CSNK2A1,PLCG1,SHC1,GRB2
FOUNDER_NAMES