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     See license terms at www.gsea-msigdb.org/gsea/license_terms_list. Please note that certain gene sets have special access terms.
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<MSIGDB BUILD_DATE="Jan 29, 2026" VERSION="2026.1.Hs" NAME="export">
    <GENESET STANDARD_NAME="BIOCARTA_IL17_PATHWAY" SYSTEMATIC_NAME="M19422" HISTORICAL_NAMES="" PMID="" AUTHORS="" GEOID="" EXACT_SOURCE="" GENESET_LISTING_URL="" EXTERNAL_DETAILS_URL="https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/human/h_il17Pathway.gif" CHIP="Human_RefSeq" CONTRIBUTOR="BioCarta" CONTRIBUTOR_ORG="BioCarta" DESCRIPTION_BRIEF="IL 17 Signaling Pathway" DESCRIPTION_FULL="Inflammation is a complex response involving many different cells and signaling molecules, including the secretion of the cytokine IL-17 by activated T cells. IL-17 secretion is restricted to specific subsets of T cells but the receptor for IL-17 is widely expressed throughout the body, including fibroblasts and epithelial cells. Inflammatory responses involving IL-17 probably contribute to arthritis, asthma, skin immune reactions and autoimmune disorders. Fibroblasts and other cells stimulated by IL-17 are induced themselves to secrete inflammatory and hematopoietic cytokines, including IL-6, IL-8, G-CSF and Stem Cell Factor (SCF). These cytokines in turn provoke a range of activities, including the stimulation of neutrophil proliferation and differentiation." TAGS="" MEMBERS="NM_000073,NM_000584,NM_000588,NM_000600,NM_000616,NM_000732,NM_000733,NM_000734,NM_000759,NM_000899,NM_001025109,NM_001040651,NM_001144822,NM_001145873,NM_001178147,NM_001195014,NM_001195015,NM_001195016,NM_001195017,NM_001767,NM_001768,NM_001773,NM_001779,NM_002190,NM_003994,NM_171827,NM_172219,NM_172220,NM_198053" MEMBERS_SYMBOLIZED="CD2,CD247,CD34,CD3D,CD3E,CD3G,CD4,CD58,CD8A,CSF3,CXCL8,IL17A,IL3,IL6,KITLG" MEMBERS_EZID="1440,3562,3569,3576,3605,4254,914,915,916,917,919,920,925,947,965" MEMBERS_MAPPING="NM_000073,CD3G,917|NM_000584,CXCL8,3576|NM_000588,IL3,3562|NM_000600,IL6,3569|NM_000616,CD4,920|NM_000732,CD3D,915|NM_000733,CD3E,916|NM_000734,CD247,919|NM_000759,CSF3,1440|NM_000899,KITLG,4254|NM_001025109,CD34,947|NM_001040651,CD3D,915|NM_001144822,CD58,965|NM_001145873,CD8A,925|NM_001178147,CSF3,1440|NM_001195014,CD4,920|NM_001195015,CD4,920|NM_001195016,CD4,920|NM_001195017,CD4,920|NM_001767,CD2,914|NM_001768,CD8A,925|NM_001773,CD34,947|NM_001779,CD58,965|NM_002190,IL17A,3605|NM_003994,KITLG,4254|NM_171827,CD8A,925|NM_172219,CSF3,1440|NM_172220,CSF3,1440|NM_198053,CD247,919" FILTERED_BY_SIMILARITY="" FOUNDER_NAMES="" REFINEMENT_DATASETS="" VALIDATION_DATASETS="" CATEGORY_CODE="C2" ORGANISM="Homo sapiens" SUB_CATEGORY_CODE="CP:BIOCARTA"/>
</MSIGDB>
