STANDARD_NAME	DESCARTES_FETAL_STOMACH_STROMAL_CELLS
SYSTEMATIC_NAME	M40304
COLLECTION	C8
MSIGDB_URL	https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/DESCARTES_FETAL_STOMACH_STROMAL_CELLS
NAMESPACE	Human_Ensembl_Gene_ID
DESCRIPTION_BRIEF	Marker genes curated from the annotated cluster as represented in the Descartes Human Gene Expression During Development database.
DESCRIPTION_FULL	The gene expression program underlying the specification of human cell types is of fundamental interest. The study authors generated human cell atlases of gene expression and chromatin accessibility in fetal tissues. For gene expression, the study authors applied three-level combinatorial indexing to >110 samples representing 15 organs, ultimately profiling ~4 million single cells. The study authors leveraged the literature and other atlases to identify and annotate hundreds of cell types and subtypes, both within and across tissues. Our analyses focused on organ-specific specializations of broadly distributed cell types (such as blood, endothelial, and epithelial), sites of fetal erythropoiesis (which notably included the adrenal gland), and integration with mouse developmental atlases (such as conserved specification of blood cells). These data represent a rich resource for the exploration of in vivo human gene expression in diverse tissues and cell types.
PMID	33184181
GEOID	GSE156793
AUTHORS	Cao J,O'Day DR,Pliner HA,Kingsley PD,Deng M,Daza RM,Zager MA,Aldinger KA,Blecher-Gonen R,Zhang F,Spielmann M,Palis J,Doherty D,Steemers FJ,Glass IA,Trapnell C,Shendure J
CONTRIBUTOR	Anthony Castanza
CONTRIBUTOR_ORG	MSigDB Team
EXACT_SOURCE	descartes DE_gene_by_organ.csv, fold.change>5, qval<0.05, pval<0.05
FILTERED_BY_SIMILARITY	
EXTERNAL_NAMES_FOR_SIMILAR_TERMS	
EXTERNAL_DETAILS_URL	https://descartes.brotmanbaty.org/bbi/human-gene-expression-during-development/
SOURCE_MEMBERS	ENSG00000004776,ENSG00000011465,ENSG00000077274,ENSG00000077942,ENSG00000101955,ENSG00000103241,ENSG00000104321,ENSG00000107796,ENSG00000108821,ENSG00000112175,ENSG00000112559,ENSG00000112936,ENSG00000116194,ENSG00000122641,ENSG00000122691,ENSG00000123572,ENSG00000130176,ENSG00000130812,ENSG00000133392,ENSG00000134853,ENSG00000137273,ENSG00000137809,ENSG00000138080,ENSG00000143196,ENSG00000145423,ENSG00000145824,ENSG00000149591,ENSG00000156689,ENSG00000160951,ENSG00000163017,ENSG00000163359,ENSG00000164530,ENSG00000164920,ENSG00000165973,ENSG00000166482,ENSG00000168079,ENSG00000168542,ENSG00000170419,ENSG00000174332,ENSG00000174807,ENSG00000175898,ENSG00000178343,ENSG00000183160,ENSG00000185920,ENSG00000189129,ENSG00000189184,ENSG00000221818,ENSG00000223561,ENSG00000224223,ENSG00000233214,ENSG00000233608,ENSG00000253864,ENSG00000264433,ENSG00000268388,ENSG00000269936
GENE_SYMBOLS	HSPB6,DCN,CAPN6,FBLN1,SRPX,FOXF1,TRPA1,ACTA2,COL1A1,BMP5,MDFI,C7,ANGPTL1,INHBA,TWIST1,NRK,CNN1,ANGPTL6,MYH11,PDGFRA,FOXF2,ITGA11,EMILIN1,DPT,SFRP2,CXCL14,TAGLN,GLYATL2,PTGER1,ACTG2,COL6A3,PI16,OSR2,NELL1,MFAP4,SCARA5,COL3A1,VSTM2A,GLIS1,CD248,,SHISA3,TMEM119,PTCH1,PLAC9,PCDH18,EBF2,LINC03007,VSTM2A-OT1,,TWIST2,,,FENDRR,
FOUNDER_NAMES	
