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<MSIGDB BUILD_DATE="Jan 29, 2026" VERSION="2026.1.Hs" NAME="export">
    <GENESET STANDARD_NAME="FAN_OVARY_CL3_MATURE_CUMULUS_GRANULOSA_CELL_1" SYSTEMATIC_NAME="M41705" HISTORICAL_NAMES="" PMID="31320652" AUTHORS="Fan X,Bialecka M,Moustakas I,Lam E,Torrens-Juaneda V,Borggreven NV,Trouw L,Louwe LA,Pilgram GSK,Mei H,van der Westerlaken L,Chuva de Sousa Lopes SM" GEOID="GSE118127" EXACT_SOURCE="Supplementary Data 2 (complete underlying data received from authors), avg_logFC &gt; 0.25, p_val_adj &lt;0.05" GENESET_LISTING_URL="" EXTERNAL_DETAILS_URL="https://doi.org/10.1038/s41467-019-11036-9" CHIP="HUMAN_GENE_SYMBOL" CONTRIBUTOR="Anthony Castanza" CONTRIBUTOR_ORG="MSigDB Team" DESCRIPTION_BRIEF="Pseudotime analysis using Monocle 3 alpha, that places the progenitor cell population in the middle of a longer trajectory segment, revealed that pGC (CL15) branched to mural GC (CL11) and mature cumulus GC (CL8 and CL3) (Fig. 6a)." DESCRIPTION_FULL="" TAGS="" MEMBERS="ABCA8,ABLIM1,ACSL4,ACSM3,ACTG1,AKAP9,AMH,ANXA6,APOA1,ARPC2,ATP5G2,ATP5I,ATP5J,ATP5J2,ATPIF1,ATRX,AVPI1,BAMBI,BAX,BEX1,BEX4,BMPR2,BTF3L4,C11orf31,C14orf2,C4orf48,C7orf73,C9orf16,CAMTA1,CBX3,CCND2,CD47,CD99,CDH2,CFI,CKB,CLDN11,CLIC1,CLNS1A,CMTM6,CNOT7,COL4A1,COL4A2,COX5B,COX6B1,COX7C,CST3,DAAM1,DAG1,DAPL1,DBI,DDAH2,DDX17,DONSON,DPP7,DPYSL3,DSP,DST,EIF4G1,ELK1,EML5,ENAH,EPDR1,EPHX1,FAM198B,FAM204A,FAM78A,FHL2,FKBP9,FLNA,FSCN1,FST,GABPB1-AS1,GATM,GJA1,GPX3,GRB14,GREB1,GRIK1,GSTA1,GSTA4,GSTP1,GTF2H5,GTF2I,H1F0,H3F3A,HACD3,HDAC2,HIF1A,HIGD2A,HMGN1,HNRNPD,HOPX,HS3ST1,HS6ST1,HSBP1,HSD17B1,HSPG2,HTRA1,HUWE1,ID3,IDH1,IFI27,IFI35,IGFBP2,IGFBP7,INSR,ITGB1,IVNS1ABP,KCNQ1OT1,KIDINS220,KTN1,LAPTM4B,LCMT1,LGALS3BP,LMBR1L,LPP,LSM5,LSM7,LUC7L3,LY6E,MAGED2,MALAT1,MAOB,MAP4K4,MARCKS,MARCKSL1,MDK,MEX3B,MFAP2,MGST3,MPST,MRPS21,MSI2,MT-ATP6,MT-CO1,MT-CO2,MT-CO3,MT-CYB,MT-ND1,MT-ND2,MT-ND3,MT-ND4,MT-ND4L,MT-ND5,MUM1,MYH9,MYL6,MZT2B,NDFIP1,NDP,NDUFA13,NDUFA3,NDUFB5,NDUFB7,NDUFC2,NDUFS4,NDUFS5,NEDD8,NGFRAP1,NKTR,NME4,NONO,NSG1,NUP214,OCIAD2,OSBPL1A,PABPN1,PCBP2,PEG3,PET100,PHF6,PHPT1,PLA2G12A,PLA2G16,PLD3,PLEKHJ1,PLP1,POLR2I,PPDPF,PPFIBP1,PPHLN1,PPP1R12B,PPP1R14A,PRDX2,PRDX3,PRDX4,PRKAR2B,PRR15,PRSS23,PTRHD1,PTTG1IP,RBP1,RCN2,RHOB,RNF7,RPAIN,RPS25,S100B,SCD,SEC31A,SEMA6D,SEPP1,SERPINE2,SFRP4,SIGLEC11,SLC16A1,SLC5A3,SMS,SNRPD2,SNRPN,SOWAHC,SOX4,SPINT2,SPRR2F,SRI,SRP9,ST3GAL4,STMN1,SYNE2,TBC1D4,TBCA,TCEA3,TCEB2,THBS1,TIMM13,TM7SF2,TMEM123,TMEM258,TMEM261,TMEM97,TMEM98,TMSB10,TMSB4X,TNNI3,TRAPPC4,TSHZ2,TSPAN6,TSPAN7,TTC3,TUBB,UQCR10,UQCR11,UQCRQ,USO1,VCAN,VIT,VPS35,WASF1,WIPF3,XIST,YAP1,ZFP36L2,ZNF428" MEMBERS_SYMBOLIZED="ABCA8,ABLIM1,ACSL4,ACSM3,ACTG1,AKAP9,AMH,ANXA6,APOA1,ARPC2,ATP5IF1,ATP5MC2,ATP5ME,ATP5MF,ATP5MJ,ATP5PF,ATRX,AVPI1,BAMBI,BAX,BBLN,BEX1,BEX3,BEX4,BMPR2,BTF3L4,CAMTA1,CBX3,CCND2,CD47,CD99,CDH2,CFI,CKB,CLDN11,CLIC1,CLNS1A,CMTM6,CNOT7,COL4A1,COL4A2,COX5B,COX6B1,COX7C,CST3,DAAM1,DAG1,DAPL1,DBI,DDAH2,DDX17,DMAC1,DONSON,DPP7,DPYSL3,DSP,DST,EIF4G1,ELK1,ELOB,EML5,ENAH,EPDR1,EPHX1,FAM204A,FAM78A,FHL2,FKBP9,FLNA,FSCN1,FST,GABPB1-AS1,GASK1B,GATM,GJA1,GPX3,GRB14,GREB1,GRIK1,GSTA1,GSTA4,GSTP1,GTF2H5,GTF2I,H1-0,H3-3A,HACD3,HDAC2,HIF1A,HIGD2A,HMGN1,HNRNPD,HOPX,HS3ST1,HS6ST1,HSBP1,HSD17B1,HSPG2,HTRA1,HUWE1,ID3,IDH1,IFI27,IFI35,IGFBP2,IGFBP7,INSR,IRF4,ITGB1,IVNS1ABP,KCNQ1OT1,KIDINS220,KTN1,LAPTM4B,LCMT1,LGALS3BP,LMBR1L,LPP,LSM5,LSM7,LUC7L3,LY6E,MAGED2,MALAT1,MAOB,MAP4K4,MARCKS,MARCKSL1,MDK,MEX3B,MFAP2,MGST3,MPST,MRPS21,MSI2,MT-ATP6,MT-CO1,MT-CO2,MT-CO3,MT-CYB,MT-ND1,MT-ND2,MT-ND3,MT-ND4,MT-ND4L,MT-ND5,MYH9,MYL6,MZT2B,NDFIP1,NDP,NDUFA13,NDUFA3,NDUFB5,NDUFB7,NDUFC2,NDUFS4,NDUFS5,NEDD8,NICOL1,NKTR,NME4,NONO,NSG1,NUP214,OCIAD2,OSBPL1A,PABPN1,PCBP2,PEG3,PET100,PHF6,PHPT1,PLA2G12A,PLAAT3,PLD3,PLEKHJ1,PLP1,POLR2I,PPDPF,PPFIBP1,PPHLN1,PPP1R12B,PPP1R14A,PRDX2,PRDX3,PRDX4,PRKAR2B,PRR15,PRSS23,PTRHD1,PTTG1IP,RBP1,RCN2,RHOB,RNF7,RPAIN,RPS25,S100B,SCD,SEC31A,SELENOH,SELENOP,SEMA6D,SERPINE2,SFRP4,SIGLEC11,SLC16A1,SLC5A3,SMS,SNRPD2,SNRPN,SOWAHC,SOX4,SPINT2,SPRR2F,SRI,SRP9,ST3GAL4,STMN1,STMP1,SYNE2,TBC1D4,TBCA,TCEA3,THBS1,TIMM13,TM7SF2,TMEM123,TMEM258,TMEM97,TMEM98,TMSB10,TMSB4X,TNNI3,TRAPPC4,TSHZ2,TSPAN6,TSPAN7,TTC3,TUBB,UQCR10,UQCR11,UQCRQ,USO1,VCAN,VIT,VPS35,WASF1,WIPF3,XIST,YAP1,ZFP36L2,ZNF428" MEMBERS_EZID="1000,100129387,100131801,10075,10109,10142,10351,10413,10468,10521,10549,10625,10653,10916,10935,10975,10984,11098,11145,11328,11335,114132,114876,114908,1152,1192,1207,124540,126299,1282,1284,128553,132299,1329,1340,1350,1462,1471,1605,161436,1622,1809,1832,192286,1981,2002,203068,2052,2182,222171,2274,22872,23002,2316,23224,23261,23564,23646,23658,25805,26022,2628,26517,268,2697,27018,27065,27089,27346,280636,286336,2878,2888,2897,29085,2938,2941,2950,2969,29796,29883,29952,29980,3005,3020,3066,309,3091,3150,3184,3281,3292,3339,335,3399,3417,3426,3429,3430,3485,3490,3643,3662,3688,378938,388,3895,391356,3925,3959,3983,401115,4026,404672,4061,4082,4129,4192,4237,4259,4267,4357,4508,4512,4513,4514,4519,4535,4536,4537,4538,4539,4540,4627,4637,4660,4693,4696,4711,4713,4718,4724,4725,4738,4820,4833,4841,5010,5094,51079,51313,51399,51451,51495,51535,51690,517,51747,5178,521,5212,522,5270,5354,5438,54460,546,54749,54918,55111,55353,55716,55737,55740,5577,55859,56271,5654,57498,581,5947,5955,60370,6230,6285,6296,6319,63877,6414,6424,644150,647087,6484,65108,65124,6526,6566,659,6611,6624,6633,6638,6659,667,6705,6717,6726,678,6902,6920,6923,7001,7057,71,7102,7105,7108,7114,7137,7267,746,7503,754,79095,79144,80031,80097,8021,80762,8106,81579,84206,84268,84295,84525,8496,8615,8936,894,90871,91408,9168,92196,9394,93974,94274,9448,9551,9556,961,9616,9687,9882,9957" MEMBERS_MAPPING="ABCA8,ABCA8,10351|ABLIM1,ABLIM1,3983|ACSL4,ACSL4,2182|ACSM3,ACSM3,6296|ACTG1,ACTG1,71|AKAP9,AKAP9,10142|AMH,AMH,268|ANXA6,ANXA6,309|APOA1,APOA1,335|ARPC2,ARPC2,10109|ATP5G2,ATP5MC2,517|ATP5I,ATP5ME,521|ATP5J,ATP5PF,522|ATP5J2,ATP5MF,9551|ATPIF1,ATP5IF1,93974|ATRX,ATRX,546|AVPI1,AVPI1,60370|BAMBI,BAMBI,25805|BAX,BAX,581|BEX1,BEX1,55859|BEX4,BEX4,56271|BMPR2,BMPR2,659|BTF3L4,BTF3L4,91408|C11orf31,SELENOH,280636|C14orf2,ATP5MJ,9556|C4orf48,NICOL1,401115|C7orf73,STMP1,647087|C9orf16,BBLN,79095|CAMTA1,CAMTA1,23261|CBX3,CBX3,11335|CCND2,CCND2,894|CD47,CD47,961|CD99,CD99,4267|CDH2,CDH2,1000|CFI,CFI,3426|CKB,CKB,1152|CLDN11,CLDN11,5010|CLIC1,CLIC1,1192|CLNS1A,CLNS1A,1207|CMTM6,CMTM6,54918|CNOT7,CNOT7,29883|COL4A1,COL4A1,1282|COL4A2,COL4A2,1284|COX5B,COX5B,1329|COX6B1,COX6B1,1340|COX7C,COX7C,1350|CST3,CST3,1471|DAAM1,DAAM1,23002|DAG1,DAG1,1605|DAPL1,DAPL1,92196|DBI,DBI,1622|DDAH2,DDAH2,23564|DDX17,DDX17,10521|DONSON,DONSON,29980|DPP7,DPP7,29952|DPYSL3,DPYSL3,1809|DSP,DSP,1832|DST,DST,667|EIF4G1,EIF4G1,1981|ELK1,ELK1,2002|EML5,EML5,161436|ENAH,ENAH,55740|EPDR1,EPDR1,54749|EPHX1,EPHX1,2052|FAM198B,GASK1B,51313|FAM204A,FAM204A,63877|FAM78A,FAM78A,286336|FHL2,FHL2,2274|FKBP9,FKBP9,11328|FLNA,FLNA,2316|FSCN1,FSCN1,6624|FST,FST,10468|GABPB1-AS1,GABPB1-AS1,100129387|GATM,GATM,2628|GJA1,GJA1,2697|GPX3,GPX3,2878|GRB14,GRB14,2888|GREB1,GREB1,9687|GRIK1,GRIK1,2897|GSTA1,GSTA1,2938|GSTA4,GSTA4,2941|GSTP1,GSTP1,2950|GTF2H5,GTF2H5,404672|GTF2I,GTF2I,2969|H1F0,H1-0,3005|H3F3A,H3-3A,3020|HACD3,HACD3,51495|HDAC2,HDAC2,3066|HIF1A,HIF1A,3091|HIGD2A,HIGD2A,192286|HMGN1,HMGN1,3150|HNRNPD,HNRNPD,3184|HOPX,HOPX,84525|HS3ST1,HS3ST1,9957|HS6ST1,HS6ST1,9394|HSBP1,HSBP1,3281|HSD17B1,HSD17B1,3292|HSPG2,HSPG2,3339|HTRA1,HTRA1,5654|HUWE1,HUWE1,10075|ID3,ID3,3399|IDH1,IDH1,3417|IFI27,IFI27,3429|IFI35,IFI35,3430|IGFBP2,IGFBP2,3485|IGFBP7,IGFBP7,3490|INSR,INSR,3643|ITGB1,ITGB1,3688|IVNS1ABP,IVNS1ABP,10625|KCNQ1OT1,KCNQ1OT1,10984|KIDINS220,KIDINS220,57498|KTN1,KTN1,3895|LAPTM4B,LAPTM4B,55353|LCMT1,LCMT1,51451|LGALS3BP,LGALS3BP,3959|LMBR1L,LMBR1L,55716|LPP,LPP,4026|LSM5,LSM5,23658|LSM7,LSM7,51690|LUC7L3,LUC7L3,51747|LY6E,LY6E,4061|MAGED2,MAGED2,10916|MALAT1,MALAT1,378938|MAOB,MAOB,4129|MAP4K4,MAP4K4,9448|MARCKS,MARCKS,4082|MARCKSL1,MARCKSL1,65108|MDK,MDK,4192|MEX3B,MEX3B,84206|MFAP2,MFAP2,4237|MGST3,MGST3,4259|MPST,MPST,4357|MRPS21,MRPS21,54460|MSI2,MSI2,124540|MT-ATP6,MT-ATP6,4508|MT-CO1,MT-CO1,4512|MT-CO2,MT-CO2,4513|MT-CO3,MT-CO3,4514|MT-CYB,MT-CYB,4519|MT-ND1,MT-ND1,4535|MT-ND2,MT-ND2,4536|MT-ND3,MT-ND3,4537|MT-ND4,MT-ND4,4538|MT-ND4L,MT-ND4L,4539|MT-ND5,MT-ND5,4540|MUM1,IRF4,3662|MYH9,MYH9,4627|MYL6,MYL6,4637|MZT2B,MZT2B,80097|NDFIP1,NDFIP1,80762|NDP,NDP,4693|NDUFA13,NDUFA13,51079|NDUFA3,NDUFA3,4696|NDUFB5,NDUFB5,4711|NDUFB7,NDUFB7,4713|NDUFC2,NDUFC2,4718|NDUFS4,NDUFS4,4724|NDUFS5,NDUFS5,4725|NEDD8,NEDD8,4738|NGFRAP1,BEX3,27018|NKTR,NKTR,4820|NME4,NME4,4833|NONO,NONO,4841|NSG1,NSG1,27065|NUP214,NUP214,8021|OCIAD2,OCIAD2,132299|OSBPL1A,OSBPL1A,114876|PABPN1,PABPN1,8106|PCBP2,PCBP2,5094|PEG3,PEG3,5178|PET100,PET100,100131801|PHF6,PHF6,84295|PHPT1,PHPT1,29085|PLA2G12A,PLA2G12A,81579|PLA2G16,PLAAT3,11145|PLD3,PLD3,23646|PLEKHJ1,PLEKHJ1,55111|PLP1,PLP1,5354|POLR2I,POLR2I,5438|PPDPF,PPDPF,79144|PPFIBP1,PPFIBP1,8496|PPHLN1,PPHLN1,51535|PPP1R12B,PPP1R12B,4660|PPP1R14A,PPP1R14A,94274|PRDX2,PRDX2,7001|PRDX3,PRDX3,10935|PRDX4,PRDX4,10549|PRKAR2B,PRKAR2B,5577|PRR15,PRR15,222171|PRSS23,PRSS23,11098|PTRHD1,PTRHD1,391356|PTTG1IP,PTTG1IP,754|RBP1,RBP1,5947|RCN2,RCN2,5955|RHOB,RHOB,388|RNF7,RNF7,9616|RPAIN,RPAIN,84268|RPS25,RPS25,6230|S100B,S100B,6285|SCD,SCD,6319|SEC31A,SEC31A,22872|SEMA6D,SEMA6D,80031|SEPP1,SELENOP,6414|SERPINE2,SERPINE2,5270|SFRP4,SFRP4,6424|SIGLEC11,SIGLEC11,114132|SLC16A1,SLC16A1,6566|SLC5A3,SLC5A3,6526|SMS,SMS,6611|SNRPD2,SNRPD2,6633|SNRPN,SNRPN,6638|SOWAHC,SOWAHC,65124|SOX4,SOX4,6659|SPINT2,SPINT2,10653|SPRR2F,SPRR2F,6705|SRI,SRI,6717|SRP9,SRP9,6726|ST3GAL4,ST3GAL4,6484|STMN1,STMN1,3925|SYNE2,SYNE2,23224|TBC1D4,TBC1D4,9882|TBCA,TBCA,6902|TCEA3,TCEA3,6920|TCEB2,ELOB,6923|THBS1,THBS1,7057|TIMM13,TIMM13,26517|TM7SF2,TM7SF2,7108|TMEM123,TMEM123,114908|TMEM258,TMEM258,746|TMEM261,DMAC1,90871|TMEM97,TMEM97,27346|TMEM98,TMEM98,26022|TMSB10,TMSB10,9168|TMSB4X,TMSB4X,7114|TNNI3,TNNI3,7137|TRAPPC4,TRAPPC4,51399|TSHZ2,TSHZ2,128553|TSPAN6,TSPAN6,7105|TSPAN7,TSPAN7,7102|TTC3,TTC3,7267|TUBB,TUBB,203068|UQCR10,UQCR10,29796|UQCR11,UQCR11,10975|UQCRQ,UQCRQ,27089|USO1,USO1,8615|VCAN,VCAN,1462|VIT,VIT,5212|VPS35,VPS35,55737|WASF1,WASF1,8936|WIPF3,WIPF3,644150|XIST,XIST,7503|YAP1,YAP1,10413|ZFP36L2,ZFP36L2,678|ZNF428,ZNF428,126299" FILTERED_BY_SIMILARITY="" FOUNDER_NAMES="" REFINEMENT_DATASETS="" VALIDATION_DATASETS="" CATEGORY_CODE="C8" ORGANISM="Homo sapiens" SUB_CATEGORY_CODE=""/>
</MSIGDB>
