STANDARD_NAME	GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN
SYSTEMATIC_NAME	M3130
COLLECTION	C7:IMMUNESIGDB
MSIGDB_URL	https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN
NAMESPACE	HUMAN_GENE_SYMBOL
DESCRIPTION_BRIEF	Genes down-regulated in comparison of untreated macrophages versus those cultured with M-CSF [GeneID=1435] and Pam3Cys (TLR2 agonist).
DESCRIPTION_FULL	Gene expression analysis of freshly isolated CD14+ human monocytes and monocytes cultured in the presence or absence of interferon (IFN) -gamma for 24 h and then stimulated with Pam3Cys, a Toll-like receptor (TLR) 2 ligand, for 6 h. Results provide insight into mechanisms by which IFN-gamma reprograms early macrophage differentiation and subsequent response to TLR ligands.
PMID	18976936
GEOID	GSE11864
AUTHORS	Hu X,Chung AY,Wu I,Foldi J,Chen J,Ji JD,Tateya T,Kang YJ,Han J,Gessler M,Kageyama R,Ivashkiv LB
CONTRIBUTOR	Jernej Godec
CONTRIBUTOR_ORG	Dana-Farber Cancer Institute
EXACT_SOURCE	GSE11864_1080_200_DN
FILTERED_BY_SIMILARITY	
EXTERNAL_NAMES_FOR_SIMILAR_TERMS	
EXTERNAL_DETAILS_URL	
SOURCE_MEMBERS	ACP5,AGRN,ANKRD1,APTX,ATXN7L3B,B4GALNT2,BACH1,BARX1,BCAT1,C10orf108,C12orf44,C14orf80,C16orf52,C1QTNF1,C20orf20,C2orf44,C6orf108,C7orf68,C9orf79,CASC3,CBFB,CC2D1B,CCDC79,CCDC99,CDH9,CDKN2B-AS1,CDON,CHRNA10,CKAP2L,CLEC3A,CLK2,CNOT4,CNRIP1,COL23A1,CPSF2,CRLF2,CSNK1A1P1,CTSL1P8,DCAF4L1,DCLRE1B,DDX23,DENND4B,DOCK1,DTX2,DTX4,DYNLT3,EDEM1,EGLN2,EIF5B,ELP2,ELP3,EMD,EML4,EPB41L5,ERRFI1,FAM114A2,FAM176A,FNDC3B,GADD45B,GAR1,GPT2,GRWD1,HCN4,HEATR2,HIVEP3,HNMT,HSDL1,HSPB1,IBTK,IFRD2,IKBKG,IL3RA,IMMT,IPO9,IRF6,JUB,KHDRBS3,KHNYN,KIAA0664,KLHL23,KLHL28,KLHL9,KPNA3,KRT14,KRT222,KRTAP3-1,LEO1,LMAN1,LOC100131541,LOC158434,LOC283104,LOC400657,LOC400692,LOC541472,LOC728431,LOC729658,LSG1,MARCH9,MCCC2,MDFIC,MEGF8,MFAP3,MKI67IP,MRPL3,MRPL46,MTHFD2L,MTMR2,MUCL1,MYOCD,NAA50,NIM1,NIP7,NOP56,NPTN,NUP35,NXT2,PAK1IP1,PDE7A,PFKP,PHF23,PIK3AP1,PLAGL2,POLR1C,PPP1R11,PPP2R1A,PROM1,PSKH1,PSMA1,PSMB4,PSMC3,PSMC4,PSMD3,RANBP1,RASA3,RBM28,RHO,RMI1,RRAGA,RYBP,SAMD15,SCN1B,SCO1,SEC61A1,SEC61G,SEPHS2,SERINC1,SFT2D2,SIGLEC1,SLC30A1,SLC44A4,SMG7,SNRPD3,SNRPG,SPATA9,SPATS2L,SRC,STAM2,SYT1,TAF9,TIFAB,TINF2,TLR1,TMEM165,TMEM208,TMEM41B,TMEM69,TMPRSS2,TMUB1,TNFRSF14,TOM1,TRIM45,TSG101,TXNDC9,TXNL4B,UBE2DNL,UGP2,UGT2B15,UNC50,USP36,UTP18,VDAC1,VPS33A,WDR5B,WFDC1,WIZ,XPO5,YARS2,ZHX2,ZKSCAN5,ZMYND15,ZNF227,ZNF233,ZNF234,ZNF235,ZNF302,ZNF613,ZNF624,ZNF672,ZNF701,ZW10
GENE_SYMBOLS	ACP5,AGRN,ANKRD1,APTX,ATXN7L3B,B4GALNT2,BACH1,BARX1,BCAT1,DIP2C-AS1,ATG101,TEDC1,MOSMO,C1QTNF1,MRGBP,WDCP,DNPH1,HILPDA,SPATA31E1,CASC3,CBFB,CC2D1B,TERB1,SPDL1,CDH9,CDKN2B-AS1,CDON,CHRNA10,CKAP2L,CLEC3A,CLK2,CNOT4,CNRIP1,COL23A1,CPSF2,CRLF2,CSNK1A1P1,CTSLP8,DCAF4L1,DCLRE1B,DDX23,DENND4B,DOCK1,DTX2,DTX4,DYNLT3,EDEM1,EGLN2,EIF5B,ELP2,ELP3,EMD,EML4,EPB41L5,ERRFI1,FAM114A2,EVA1A,FNDC3B,GADD45B,GAR1,GPT2,GRWD1,HCN4,DNAAF5,HIVEP3,HNMT,HSDL1,HSPB1,IBTK,IFRD2,IKBKG,IL3RA,IMMT,IPO9,IRF6,AJUBA,KHDRBS3,KHNYN,CLUH,KLHL23,KLHL28,KLHL9,KPNA3,KRT14,KRT222,KRTAP3-1,LEO1,LMAN1,,ENSG00000275465,SBF2-AS1,ZNF407-AS1,,IL6-AS1,LITATS1,PACRG-AS3,LSG1,MARCHF9,MCCC2,MDFIC,MEGF8,MFAP3,NIFK,MRPL3,MRPL46,MTHFD2L,MTMR2,MUCL1,MYOCD,NAA50,NIM1K,NIP7,NOP56,NPTN,NUP35,NXT2,PAK1IP1,PDE7A,PFKP,PHF23,PIK3AP1,PLAGL2,POLR1C,PPP1R11,PPP2R1A,PROM1,PSKH1,PSMA1,PSMB4,PSMC3,PSMC4,PSMD3,RANBP1,RASA3,RBM28,RHO,RMI1,RRAGA,RYBP,SAMD15,SCN1B,SCO1,SEC61A1,SEC61G,SEPHS2,SERINC1,SFT2D2,SIGLEC1,SLC30A1,SLC44A4,SMG7,SNRPD3,SNRPG,SPATA9,SPATS2L,SRC,STAM2,SYT1,TAF9,TIFAB,TINF2,TLR1,TMEM165,TMEM208,TMEM41B,TMEM69,TMPRSS2,TMUB1,TNFRSF14,TOM1,TRIM45,TSG101,TXNDC9,TXNL4B,UBE2DNL,UGP2,UGT2B15,UNC50,USP36,UTP18,VDAC1,VPS33A,WDR5B,WFDC1,WIZ,XPO5,YARS2,ZHX2,ZKSCAN5,ZMYND15,ZNF227,ZNF233,ZNF234,ZNF235,ZNF302,ZNF613,ZNF624,ZNF672,ZNF701,ZW10
FOUNDER_NAMES