STANDARD_NAME	GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_DN
SYSTEMATIC_NAME	M8106
COLLECTION	C7:IMMUNESIGDB
MSIGDB_URL	https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_DN
NAMESPACE	HUMAN_GENE_SYMBOL
DESCRIPTION_BRIEF	Genes down-regulated in IL10 [GeneID=3586] knockout macrophages: unstimulated versus LPS.
DESCRIPTION_FULL	Bone marrow-derived macrophages were produced from mice lacking IL-10 alone (IL10-def) or mice lacking both IL-10 and the p50/p105 subunit of NF-kB (p50/IL10), and left unstimulated, stimulated with LPS (1 ng/ml) or stimulated with LPS and IL-10 (0.3 ng/ml).
PMID	21217011
GEOID	GSE19941
AUTHORS	Yang HT,Wang Y,Zhao X,Demissie E,Papoutsopoulou S,Mambole A,O'Garra A,Tomczak MF,Erdman SE,Fox JG,Ley SC,Horwitz BH
CONTRIBUTOR	Jernej Godec
CONTRIBUTOR_ORG	Dana-Farber Cancer Institute
EXACT_SOURCE	GSE19941_3666_200_DN
FILTERED_BY_SIMILARITY	
EXTERNAL_NAMES_FOR_SIMILAR_TERMS	
EXTERNAL_DETAILS_URL	
SOURCE_MEMBERS	AFF3,AFMID,AK2,ANKDD1B,ANKRD29,ANKRD44,ANKRD6,ANTXR2,ANUBL1,ANXA1,APLP2,APOBEC1,ARHGAP19,ARID2,ARRDC3,ATP2B1,B4GALT4,BCAS2,BCL9,BEX1,BTD,BTK,C11orf30,C16orf73,C16orf80,C20orf196,C2orf69,C3orf67,CACNA1E,CCDC14,CCDC34,CCR8,CD1D,CD83,CD84,CDC25B,CDH1,CELF2,CEP192,CEP70,CEP89,CETN2,CHAC2,CHEK2,CHTOP,CKAP5,CNIH3,COG5,CPA6,CPSF6,CSK,CST3,DCP2,DDX26B,DEF8,DHX34,DIAPH2,DOK2,DPYSL2,DUSP10,DUSP4,DUSP5,EHHADH,EMR1,ENTPD5,EPDR1,EVI2A,EVL,EWSR1,EXOSC3,F8,FABP7,FAM20B,FAM26F,FBLN1,FGD6,FGF13,FGF21,GABPA,GBX1,GCAT,GPC6,GPR174,GPR34,GTPBP1,HAUS8,HEXIM2,HJURP,HNRNPUL2,HS3ST1,IFI44L,IFIT2,IFT172,IL10RB,IL17RB,ITGB3,IVD,KATNB1,KCNMB2,KLF4,KLHL33,KRBA1,KYNU,LOC100288797,LRRC40,LRRCC1,LSP1,MCART1,MCART6,MDH1,METTL19,MMP12,MORC3,MRPL39,MST1R,N4BP2L2,NCF2,NCOA2,NCOA7,NEO1,NKAP,NME7,NSUN4,NUDT16L1,OGDH,OSGEP,OTUB2,PAQR4,PARP1,PDE1A,PDE8A,PDHB,PDLIM2,PENK,PEX19,PHC1,PIAS1,PIP5K1B,PMEL,PNPLA3,PRDM2,PRKAG2,PRKAR2B,PRKCDBP,PSMA5,PSMB4,PSMB6,PSMB7,RASA1,RASAL1,RPRD1A,S100A8,S100PBP,SERPINC1,SESN1,SFMBT1,SFMBT2,SH2D3C,SH3BGRL,SIAE,SIK1,SIN3A,SIP1,SIX5,SIX6,SLC25A40,SLC25A45,SLC4A7,SMARCA4,SMARCC2,SMC4,SNRPA,SNX3,ST8SIA6,STK39,STT3B,SVIL,TANC2,TANK,TBC1D30,TEAD1,TFCP2,TMC4,TMCC1,TNFAIP8L1,TRAF5,TRIM44,TRIM59,TROAP,TTC35,UBR7,URGCP,USP47,VRK2,VSIG2,WLS,XIAP,ZNF389,ZNF569,ZNF619
GENE_SYMBOLS	AFF3,AFMID,AK2,ANKDD1B,ANKRD29,ANKRD44,ANKRD6,ANTXR2,ZFAND4,ANXA1,APLP2,APOBEC1,ARHGAP19,ARID2,ARRDC3,ATP2B1,B4GALT4,BCAS2,BCL9,BEX1,BTD,BTK,EMSY,MEIOB,CFAP20,SHLD1,C2orf69,CFAP20DC,CACNA1E,CCDC14,CCDC34,CCR8,CD1D,CD83,CD84,CDC25B,CDH1,CELF2,CEP192,CEP70,CEP89,CETN2,CHAC2,CHEK2,CHTOP,CKAP5,CNIH3,COG5,CPA6,CPSF6,CSK,CST3,DCP2,INTS6L,DEF8,DHX34,DIAPH2,DOK2,DPYSL2,DUSP10,DUSP4,DUSP5,EHHADH,ADGRE1,ENTPD5,EPDR1,EVI2A,EVL,EWSR1,EXOSC3,F8,FABP7,FAM20B,CALHM6,FBLN1,FGD6,FGF13,FGF21,GABPA,GBX1,GCAT,GPC6,GPR174,GPR34,GTPBP1,HAUS8,HEXIM2,HJURP,HNRNPUL2,HS3ST1,IFI44L,IFIT2,IFT172,IL10RB,IL17RB,ITGB3,IVD,KATNB1,KCNMB2,KLF4,KLHL33,KRBA1,KYNU,TMEM239,LRRC40,LRRCC1,LSP1,SLC25A51,SLC25A53,MDH1,TRMT44,MMP12,MORC3,MRPL39,MST1R,N4BP2L2,NCF2,NCOA2,NCOA7,NEO1,NKAP,NME7,NSUN4,NUDT16L1,OGDH,OSGEP,OTUB2,PAQR4,PARP1,PDE1A,PDE8A,PDHB,PDLIM2,PENK,PEX19,PHC1,PIAS1,PIP5K1B,PMEL,PNPLA3,PRDM2,PRKAG2,PRKAR2B,CAVIN3,PSMA5,PSMB4,PSMB6,PSMB7,RASA1,RASAL1,RPRD1A,S100A8,S100PBP,SERPINC1,SESN1,SFMBT1,SFMBT2,SH2D3C,SH3BGRL,SIAE,SIK1,SIN3A,GEMIN2,SIX5,SIX6,SLC25A40,SLC25A45,SLC4A7,SMARCA4,SMARCC2,SMC4,SNRPA,SNX3,ST8SIA6,STK39,STT3B,SVIL,TANC2,TANK,TBC1D30,TEAD1,TFCP2,TMC4,TMCC1,TNFAIP8L1,TRAF5,TRIM44,TRIM59,TROAP,EMC2,UBR7,URGCP,USP47,VRK2,VSIG2,WLS,XIAP,ZKSCAN8P1,ZNF569,ZNF619
FOUNDER_NAMES