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     See license terms at www.gsea-msigdb.org/gsea/license_terms_list. Please note that certain gene sets have special access terms.
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<MSIGDB BUILD_DATE="Jan 29, 2026" VERSION="2026.1.Hs" NAME="export">
    <GENESET STANDARD_NAME="GSE22886_IL2_VS_IL15_STIM_NKCELL_UP" SYSTEMATIC_NAME="M4514" HISTORICAL_NAMES="" PMID="15789058" AUTHORS="Abbas AR,Baldwin D,Ma Y,Ouyang W,Gurney A,Martin F,Fong S,van Lookeren Campagne M,Godowski P,Williams PM,Chan AC,Clark HF" GEOID="GSE22886" EXACT_SOURCE="GSE22886_1666_200_UP" GENESET_LISTING_URL="" EXTERNAL_DETAILS_URL="" CHIP="HUMAN_GENE_SYMBOL" CONTRIBUTOR="Jernej Godec" CONTRIBUTOR_ORG="Dana-Farber Cancer Institute" DESCRIPTION_BRIEF="Genes up-regulated in comparison of NK cells stimulated with IL2 [GeneID=3558] at 16 h versus NK cells stimulated with IL15 [GeneID=3600] at 16 h." DESCRIPTION_FULL="Immune cell-specific expression is one indication of the importance of a gene's role in the immune response. In order to identify such patterns, we set out to broadly profile gene expression in a variety of immune cells." TAGS="" MEMBERS="A4GNT,ABCA12,ADAM12,ADAMTS6,ADAMTS7,ADRB3,AGAP2,ALLC,ALX3,APOA4,APP,AREG,ARG2,ASB4,ASGR1,ATP6V0A4,ATP8B3,B3GNT3,BAAT,BACE2,BCKDHA,BCMO1,BEST2,C1orf56,C1S,C3orf36,CAPN7,CASQ1,CBLN1,CCKBR,CCT8L2,CD34,CDH20,CHGB,CHIA,CHP2,CHRNA9,CHRND,CHST1,CLDN10,CLIC5,CNGB3,CNTNAP3B,COL5A2,CPZ,CREB5,CT62,DCLK1,DGCR9,DGKE,DGKG,DKFZP434C153,DSTYK,EGLN3,EPHB6,EPHX1,ESRP1,ETNK2,F2RL2,FAM174B,FKBP9,FMO6P,FRAS1,FSCN2,FXYD2,G6PC2,GARNL3,GATM,GJB1,GNAO1,GPR77,GUCY2C,HAVCR1,HIST1H2BI,HTR1A,IGLV6-57,IL19,IL1RAPL1,IL20RA,IL21,ING4,INSRR,IRX4,ITGB4,ITPR2,KCNB1,KCNH4,KCNJ14,KIAA0556,KLHL4,KRT31,KRT84,KSR1,LAMA5,LDB2,LOC100131510,LOC100287025,LOC100507605,LPO,MAGEA8,MAP3K9,MAPRE3,MBTPS2,MCCC2,ME1,MLLT10,MMP24,MPZL1,MS4A1,MYH1,NCRNA00312,NEUROG2,NIPSNAP3B,NME6,NUDT13,OR10H3,OR6A2,OS9,OSR2,PAX2,PAX5,PCBP3,PCDHA6,PCDHGB6,PCOLCE,PDE1B,PDE5A,PEG3,PHF1,PLA2G1B,PLLP,PMS2P1,PNMAL1,POU1F1,POU4F3,PP13,PQLC3,PSD3,PSORS1C2,PSRC1,PTN,PTPRZ1,RAB3D,RANBP17,RAPGEF5,RARRES1,RBM39,RIT2,RNASEH2B,RNF216,SAGE1,SCAMP5,SCG5,SEC14L5,SEMA7A,SENP3,SFRP1,SGK2,SH3PXD2A,SLC13A1,SLC22A4,SLC2A2,SLC2A9,SLC39A2,SLCO2A1,SOX1,SOX14,SPACA1,SPINLW1,SPTBN5,STRADA,SYNGR4,SYT13,SYT2,TAOK2,TAS2R16,TAS2R7,TBX3,TCTN3,TEK,TFCP2L1,THBS1,THBS2,THTPA,TIAM2,TLN2,TMPRSS11E,TPO,TRDN,TRPM3,TRPM8,TYRO3,UBOX5,VIP,VSNL1,WAC,WASF3,WDR78,ZNF480,ZNF536" MEMBERS_SYMBOLIZED="A4GNT,ABCA12,ADAM12,ADAMTS6,ADAMTS7,ADRB3,AGAP2,ALLC,ALX3,APOA4,APP,AREG,ARG2,ASB4,ASGR1,ATP6V0A4,ATP8B3,B3GNT3,BAAT,BACE2,BCKDHA,BCO1,BEST2,C1orf56,C1S,C3orf36,C5AR2,CAPN7,CASQ1,CBLN1,CCKBR,CCT8L2,CD34,CDH20,CHGB,CHIA,CHP2,CHRNA9,CHRND,CHST1,CLDN10,CLIC5,CNGB3,CNTNAP3B,COL5A2,CPZ,CREB5,CT62,DCLK1,DGCR5,DGKE,DGKG,DNAI4,DSTYK,EGLN3,EPHB6,EPHX1,EPPIN,ESRP1,ETNK2,F2RL2,FAM174B,FKBP9,FMO6P,FRAS1,FSCN2,FXYD2,G6PC2,GARNL3,GATM,GJB1,GNAO1,GUCY2C,H2BC10,HAVCR1,HTR1A,IGLV6-57,IL19,IL1RAPL1,IL20RA,IL21,ING4,INSRR,IRX4,ITGB4,ITPR2,KATNIP,KCNB1,KCNH4,KCNJ14,KLHL4,KRT31,KRT84,KSR1,LAMA5,LDB2,LGALS13,LINC00837,LPO,MAGEA8,MAP3K9,MAPRE3,MBTPS2,MCCC2,ME1,MLLT10,MMP24,MPZL1,MS4A1,MYH1,NEUROG2,NIPSNAP3B,NME6,NUDT13,OR10H3,OR6A2,OS9,OSR2,PAX2,PAX5,PCBP3,PCDHA6,PCDHGB6,PCOLCE,PDE1B,PDE5A,PEG3,PHF1,PLA2G1B,PLLP,PMS2P1,PNMA8A,POU1F1,POU4F3,PSD3,PSORS1C2,PSRC1,PTN,PTPRZ1,RAB3D,RANBP17,RAPGEF5,RARRES1,RBM39,RIT2,RNASEH2B,RNF216,SAGE1,SCAMP5,SCG5,SEC14L5,SEMA7A,SENP3,SFRP1,SGK2,SH3PXD2A,SLC13A1,SLC22A4,SLC2A2,SLC2A9,SLC39A2,SLC66A3,SLCO2A1,SOX1,SOX14,SPACA1,SPTBN5,STRADA,SYNGR4,SYT13,SYT2,TAOK2,TAS2R16,TAS2R7,TBX3,TCTN3,TEK,TFCP2L1,THBS1,THBS2,THTPA,TIAM2,TLN2,TMPRSS11E,TPO,TRDN,TRPM3,TRPM8,TYRO3,UBOX5,VIP,VSNL1,WAC,WASF3,ZNF480,ZNF536" MEMBERS_EZID="100507605,10110,10201,10331,10345,10810,10893,10956,1114,11141,11173,11174,112399,11328,1144,116039,116986,127833,1290,130814,147657,148229,150160,155,1608,170680,192683,196993,2051,2052,2151,22888,22924,23247,23362,23415,23473,23546,257,25778,25794,25825,25961,26123,26154,26168,26220,26230,2628,26532,26762,2705,27159,27202,2775,28316,28778,28983,29124,2984,29842,29949,29986,3350,337,351,3645,3691,3709,374,3745,3770,384,3881,388714,3890,3911,400451,4025,4107,4199,4293,432,4619,486,50617,5076,5079,50805,50833,50837,51090,51146,51147,5118,51322,51332,51360,5153,51666,5178,5252,5319,53405,53630,5379,53832,54039,54476,5449,5459,54714,54831,54845,54964,55224,55228,55335,55511,55584,55821,56062,56100,56142,56606,570,57119,57586,5764,57818,5803,59067,5918,593,6014,63928,63973,64087,6422,6447,64901,6514,6561,6578,6583,6656,6926,7010,7057,7058,716,7173,728577,7301,7432,7447,79054,79178,79621,79819,80036,80111,80144,8028,8038,81833,8346,83660,8403,84253,844,84722,8482,8526,8532,8534,8590,8654,869,8844,887,9019,9071,9079,9201,92335,931,9344,947,9545,9584,9586,9644,9717,9745,9771" MEMBERS_MAPPING="A4GNT,A4GNT,51146|ABCA12,ABCA12,26154|ADAM12,ADAM12,8038|ADAMTS6,ADAMTS6,11174|ADAMTS7,ADAMTS7,11173|ADRB3,ADRB3,155|AGAP2,AGAP2,116986|ALLC,ALLC,55821|ALX3,ALX3,257|APOA4,APOA4,337|APP,APP,351|AREG,AREG,374|ARG2,ARG2,384|ASB4,ASB4,51666|ASGR1,ASGR1,432|ATP6V0A4,ATP6V0A4,50617|ATP8B3,ATP8B3,148229|B3GNT3,B3GNT3,10331|BAAT,BAAT,570|BACE2,BACE2,25825|BCKDHA,BCKDHA,593|BCMO1,BCO1,53630|BEST2,BEST2,54831|C1S,C1S,716|C1orf56,C1orf56,54964|C3orf36,C3orf36,80111|CAPN7,CAPN7,23473|CASQ1,CASQ1,844|CBLN1,CBLN1,869|CCKBR,CCKBR,887|CCT8L2,CCT8L2,150160|CD34,CD34,947|CDH20,CDH20,28316|CHGB,CHGB,1114|CHIA,CHIA,27159|CHP2,CHP2,63928|CHRNA9,CHRNA9,55584|CHRND,CHRND,1144|CHST1,CHST1,8534|CLDN10,CLDN10,9071|CLIC5,CLIC5,53405|CNGB3,CNGB3,54714|CNTNAP3B,CNTNAP3B,728577|COL5A2,COL5A2,1290|CPZ,CPZ,8532|CREB5,CREB5,9586|CT62,CT62,196993|DCLK1,DCLK1,9201|DGCR9,DGCR5,26220|DGKE,DGKE,8526|DGKG,DGKG,1608|DKFZP434C153,null,null|DSTYK,DSTYK,25778|EGLN3,EGLN3,112399|EPHB6,EPHB6,2051|EPHX1,EPHX1,2052|ESRP1,ESRP1,54845|ETNK2,ETNK2,55224|F2RL2,F2RL2,2151|FAM174B,FAM174B,400451|FKBP9,FKBP9,11328|FMO6P,FMO6P,388714|FRAS1,FRAS1,80144|FSCN2,FSCN2,25794|FXYD2,FXYD2,486|G6PC2,G6PC2,57818|GARNL3,GARNL3,84253|GATM,GATM,2628|GJB1,GJB1,2705|GNAO1,GNAO1,2775|GPR77,C5AR2,27202|GUCY2C,GUCY2C,2984|HAVCR1,HAVCR1,26762|HIST1H2BI,H2BC10,8346|HTR1A,HTR1A,3350|IGLV6-57,IGLV6-57,28778|IL19,IL19,29949|IL1RAPL1,IL1RAPL1,11141|IL20RA,IL20RA,53832|IL21,IL21,59067|ING4,ING4,51147|INSRR,INSRR,3645|IRX4,IRX4,50805|ITGB4,ITGB4,3691|ITPR2,ITPR2,3709|KCNB1,KCNB1,3745|KCNH4,KCNH4,23415|KCNJ14,KCNJ14,3770|KIAA0556,KATNIP,23247|KLHL4,KLHL4,56062|KRT31,KRT31,3881|KRT84,KRT84,3890|KSR1,KSR1,8844|LAMA5,LAMA5,3911|LDB2,LDB2,9079|LOC100131510,null,null|LOC100287025,null,null|LOC100507605,LINC00837,100507605|LPO,LPO,4025|MAGEA8,MAGEA8,4107|MAP3K9,MAP3K9,4293|MAPRE3,MAPRE3,22924|MBTPS2,MBTPS2,51360|MCCC2,MCCC2,64087|ME1,ME1,4199|MLLT10,MLLT10,8028|MMP24,MMP24,10893|MPZL1,MPZL1,9019|MS4A1,MS4A1,931|MYH1,MYH1,4619|NCRNA00312,null,null|NEUROG2,NEUROG2,63973|NIPSNAP3B,NIPSNAP3B,55335|NME6,NME6,10201|NUDT13,NUDT13,25961|OR10H3,OR10H3,26532|OR6A2,OR6A2,8590|OS9,OS9,10956|OSR2,OSR2,116039|PAX2,PAX2,5076|PAX5,PAX5,5079|PCBP3,PCBP3,54039|PCDHA6,PCDHA6,56142|PCDHGB6,PCDHGB6,56100|PCOLCE,PCOLCE,5118|PDE1B,PDE1B,5153|PDE5A,PDE5A,8654|PEG3,PEG3,5178|PHF1,PHF1,5252|PLA2G1B,PLA2G1B,5319|PLLP,PLLP,51090|PMS2P1,PMS2P1,5379|PNMAL1,PNMA8A,55228|POU1F1,POU1F1,5449|POU4F3,POU4F3,5459|PP13,LGALS13,29124|PQLC3,SLC66A3,130814|PSD3,PSD3,23362|PSORS1C2,PSORS1C2,170680|PSRC1,PSRC1,84722|PTN,PTN,5764|PTPRZ1,PTPRZ1,5803|RAB3D,RAB3D,9545|RANBP17,RANBP17,64901|RAPGEF5,RAPGEF5,9771|RARRES1,RARRES1,5918|RBM39,RBM39,9584|RIT2,RIT2,6014|RNASEH2B,RNASEH2B,79621|RNF216,RNF216,54476|SAGE1,SAGE1,55511|SCAMP5,SCAMP5,192683|SCG5,SCG5,6447|SEC14L5,SEC14L5,9717|SEMA7A,SEMA7A,8482|SENP3,SENP3,26168|SFRP1,SFRP1,6422|SGK2,SGK2,10110|SH3PXD2A,SH3PXD2A,9644|SLC13A1,SLC13A1,6561|SLC22A4,SLC22A4,6583|SLC2A2,SLC2A2,6514|SLC2A9,SLC2A9,56606|SLC39A2,SLC39A2,29986|SLCO2A1,SLCO2A1,6578|SOX1,SOX1,6656|SOX14,SOX14,8403|SPACA1,SPACA1,81833|SPINLW1,EPPIN,57119|SPTBN5,SPTBN5,51332|STRADA,STRADA,92335|SYNGR4,SYNGR4,23546|SYT13,SYT13,57586|SYT2,SYT2,127833|TAOK2,TAOK2,9344|TAS2R16,TAS2R16,50833|TAS2R7,TAS2R7,50837|TBX3,TBX3,6926|TCTN3,TCTN3,26123|TEK,TEK,7010|TFCP2L1,TFCP2L1,29842|THBS1,THBS1,7057|THBS2,THBS2,7058|THTPA,THTPA,79178|TIAM2,TIAM2,26230|TLN2,TLN2,83660|TMPRSS11E,TMPRSS11E,28983|TPO,TPO,7173|TRDN,TRDN,10345|TRPM3,TRPM3,80036|TRPM8,TRPM8,79054|TYRO3,TYRO3,7301|UBOX5,UBOX5,22888|VIP,VIP,7432|VSNL1,VSNL1,7447|WAC,WAC,51322|WASF3,WASF3,10810|WDR78,DNAI4,79819|ZNF480,ZNF480,147657|ZNF536,ZNF536,9745" FILTERED_BY_SIMILARITY="" FOUNDER_NAMES="" REFINEMENT_DATASETS="" VALIDATION_DATASETS="" CATEGORY_CODE="C7" ORGANISM="Homo sapiens" SUB_CATEGORY_CODE="IMMUNESIGDB"/>
</MSIGDB>
