STANDARD_NAME	GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_UP
SYSTEMATIC_NAME	M4908
COLLECTION	C7:IMMUNESIGDB
MSIGDB_URL	https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_UP
NAMESPACE	HUMAN_GENE_SYMBOL
DESCRIPTION_BRIEF	Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those from day 7 post-vaccination.
DESCRIPTION_FULL	Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling applied to vaccinology. Here we used the systems vaccinology approach to study the molecular mechanisms underlying the innate responses to the trivalent inactivated influenza (TIV) and live attenuated influenza (LAIV) vaccination in humans, and to identify early gene signatures that predict the magnitude of the antibody responses to influenza vaccination.
PMID	21743478
GEOID	GSE29614
AUTHORS	Nakaya HI,Wrammert J,Lee EK,Racioppi L,Marie-Kunze S,Haining WN,Means AR,Kasturi SP,Khan N,Li GM,McCausland M,Kanchan V,Kokko KE,Li S,Elbein R,Mehta AK,Aderem A,Subbarao K,Ahmed R,Pulendran B
CONTRIBUTOR	Jernej Godec
CONTRIBUTOR_ORG	Dana-Farber Cancer Institute
EXACT_SOURCE	GSE29614_2207_200_UP
FILTERED_BY_SIMILARITY	
EXTERNAL_NAMES_FOR_SIMILAR_TERMS	
EXTERNAL_DETAILS_URL	
SOURCE_MEMBERS	A2ML1,ABT1,ACCN3,ACVRL1,ADAM3A,ADAMTS4,ADAMTS8,ADAMTSL3,AIF1L,AIRE,ALDH3A1,ANGPTL1,B3GNT3,BEAN1,BLOC1S3,BMP10,BMP2,BUD31,C14orf183,C19orf24,C1QB,C2CD4C,C2orf82,C3orf43,C3orf78,C4orf38,C6orf62,C7orf33,C8orf45,C8orf66,C9orf163,C9orf24,CACNA2D1,CAPN8,CCBP2,CCDC36,CD48,CELP,CES5A,CHRM5,CLCN2,CLDN16,CLPS,COL4A5,CREM,CSGALNACT2,CSNK2A2,CXorf36,CYP4A22,CYP4X1,DAB1,DAP,DDIT4,DGCR9,DKFZp434J0226,DOCK2,DSCR6,DUOX2,EDN2,ESPNL,FAM123C,FAM182A,FAM186B,FAM73A,FCN2,FGA,FGF19,FGFR3,FLG2,FLJ11292,FLJ11710,FLJ30403,FRMD6,FSHR,FUT1,GABRB1,GAD1,GALT,GDF5,GJA8,GLIS2,GNLY,GPR161,GPX5,GREM2,GRM4,HAAO,HOXA3,HOXB7,HS3ST6,HYAL2,IL11,IL22RA2,IL24,KCNK9,KRTAP1-3,KRTAP19-3,LCN6,LDHAL6A,LENEP,LOC100128640,LOC100131642,LOC100288618,LOC100288809,LOC100289494,LOC100289617,LOC100289632,LOC100294362,LOC100505545,LOC100505716,LOC100507391,LOC257152,LOC283738,LOC285281,LOC285740,LOC388946,LOC402160,LOC441025,LOC643714,MAN2B2,MATN4,MED9,MGC45800,MIRLET7BHG,MLNR,NBPF5,NCOA1,NCRNA00271,NMD3,NXNL1,OR51J1,OR7E19P,OR8G1,PAGE1,PALMD,PANX2,PARVA,PDE4A,PDHA2,PDLIM7,PEBP4,PER4,PGCP,PITX2,PKD2L2,PKHD1,PLEKHN1,POLE4,PRAC,PROCR,PRX,PTMS,PTP4A1,RACGAP1P,RAD51L1,RAET1E,RBM18,RNF215,RPL23AP53,RUSC2,RXFP2,SAG,SALL3,SEC24B,SEMA5A,SERPINB5,SIGLEC6,SIGLEC8,SLC13A4,SLC5A4,SMAP1,SNX7,SOX4,SPRR2B,SSTR2,STATH,STK4,STRN3,SYF2,TAS2R41,TCEB3B,TEAD2,TGIF1,TJP1,TLE6,TMEM63B,TMEM90A,TMX4,TOB1,TPSB2,TRPC6,UBXN10,USP25,VSTM2A,WNK3,ZDHHC2,ZNF157,ZNF408,ZNF576,ZSCAN1
GENE_SYMBOLS	A2ML1,ABT1,ASIC3,ACVRL1,ADAM3A,ADAMTS4,ADAMTS8,ADAMTSL3,AIF1L,AIRE,ALDH3A1,ANGPTL1,B3GNT3,BEAN1,BLOC1S3,BMP10,BMP2,BUD31,,FAM174C,C1QB,C2CD4C,SNORC,SMCO1,UQCC5,WWC2-AS2,C6orf62,C7orf33,MCMDC2,,C9orf163,SPMIP6,CACNA2D1,CAPN8,ACKR2,IHO1,CD48,CELP,CES5A,CHRM5,CLCN2,CLDN16,CLPS,COL4A5,CREM,CSGALNACT2,CSNK2A2,DIPK2B,CYP4A22,CYP4X1,DAB1,DAP,DDIT4,DGCR5,,DOCK2,RIPPLY3,DUOX2,EDN2,ESPNL,AMER3,FAM182A,FAM186B,MIGA1,FCN2,FGA,FGF19,FGFR3,FLG2,LINC01949,,LINC01530,FRMD6,FSHR,FUT1,GABRB1,GAD1,GALT,GDF5,GJA8,GLIS2,GNLY,GPR161,GPX5,GREM2,GRM4,HAAO,HOXA3,HOXB7,HS3ST6,HYAL2,IL11,IL22RA2,IL24,KCNK9,KRTAP1-3,KRTAP19-3,LCN6,LDHAL6A,LENEP,ACVR2B-AS1,,,,,,,RNF213-AS1,LINC01095,ENSG00000223522,LINC01968,BAALC-AS1,NTRK3-AS1,MOBP,PHACTR2-AS1,TMEM247,CFAP99,LINC02483,CASC16,MAN2B2,MATN4,MED9,,MIRLET7BHG,MLNR,NBPF5P,NCOA1,AHI1-DT,NMD3,NXNL1,OR51J1,OR7E19P,OR8G1,PAGE1,PALMD,PANX2,PARVA,PDE4A,PDHA2,PDLIM7,PEBP4,PER3P1,CPQ,PITX2,PKD2L2,PKHD1,PLEKHN1,POLE4,PRAC1,PROCR,PRX,PTMS,PTP4A1,RACGAP1P1,RAD51B,RAET1E,RBM18,RNF215,RPL23AP53,RUSC2,RXFP2,SAG,SALL3,SEC24B,SEMA5A,SERPINB5,SIGLEC6,SIGLEC8,SLC13A4,SLC5A4,SMAP1,SNX7,SOX4,SPRR2B,SSTR2,STATH,STK4,STRN3,SYF2,TAS2R41,ELOA2,TEAD2,TGIF1,TJP1,TLE6,TMEM63B,SYNDIG1L,TMX4,TOB1,TPSB2,TRPC6,UBXN10,USP25,VSTM2A,WNK3,ZDHHC2,ZNF157,ZNF408,ZNF576,ZSCAN1
FOUNDER_NAMES