STANDARD_NAME	GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_DN
SYSTEMATIC_NAME	M8993
COLLECTION	C7:IMMUNESIGDB
MSIGDB_URL	https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_DN
NAMESPACE	HUMAN_GENE_SYMBOL
DESCRIPTION_BRIEF	Genes down-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and Pparg2 isoform of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829].
DESCRIPTION_FULL	We identified Pparg as a major orchestrator of the phenotype of adipose-tissue resident regulatory T cells (VAT Tregs). To explore the contribution of Pparg1 and 2 in the generation of the VAT Tregs-specific gene signatures, CD4+FoxP3- T cells were transduced with Foxp3+/- Pparg1 (or Pparg2), treated with Pioglitazone or vehicle, and double sorted for microarray analysis.
PMID	22722857
GEOID	GSE37533
AUTHORS	Cipolletta D,Feuerer M,Li A,Kamei N,Lee J,Shoelson SE,Benoist C,Mathis D
CONTRIBUTOR	Jernej Godec
CONTRIBUTOR_ORG	Dana-Farber Cancer Institute
EXACT_SOURCE	GSE37533_2856_200_DN
FILTERED_BY_SIMILARITY	
EXTERNAL_NAMES_FOR_SIMILAR_TERMS	
EXTERNAL_DETAILS_URL	
SOURCE_MEMBERS	0610010K14Rik,1500011B03Rik,1700021K19Rik,1700054O19Rik,1700062I23Rik,1700101E01Rik,1810030N24Rik,2010012O05Rik,2610029I01Rik,2610036D13Rik,2900092E17Rik,4930486L24Rik,5031439G07Rik,5430411K18Rik,6330545A04Rik,6430527G18Rik,AB041803,ABCB10,ABTB1,ACAA1A,ACSS2,ANXA7,ARL11,ASH1L,B3GNT1,B930095G15Rik,BCKDHB,BCL7A,BCS1L,BMYC,BTBD19,C78339,CALM1,CAPN1,CASP7,CC2D1A,CCDC114,CCNG1,CFL1,CHD9,CHRNB1,CLCN3,COBLL1,COMMD2,CSTB,CTDSPL2,CTSC,CTSW,CUL3,CXX1C,CYB5R1,CYHR1,D10JHU81E,D330012F22Rik,D330038O06Rik,D330041H03Rik,DMXL2,DUSP7,E130120F12Rik,EEFSEC,EIF4B,ELOVL5,ENTPD5,FAAH,FAM105A,FAM108A,FAM109B,FAM126B,FAM174B,FAM176B,FAM53B,FCRLS,FMO5,FNIP2,FOXO4,FPR-RS3,GALNT12,GCAP14,GLUD1,GM10505,GM10838,GM15441,GM568,GM9856,GPBP1L1,GPR132,GRHPR,GYS1,H6PD,HDAC10,HIP1,HS1BP3,HSF4,HSPBAP1,ICOS,IDUA,IKZF5,JMJD4,KAT2B,KIF16B,KLF12,KRT80,LACE1,LANCL1,LETMD1,MAP4K1,MAPKBP1,MAVS,MED24,MLEC,MLF2,MOBKL2A,MPRIP,MPV17L,MRI1,MRPL40,MYO18A,NDFIP1,NDUFAF1,NDUFV1,NPRL2,PADI2,PDCD6IP,PDDC1,PET112L,PFKFB4,PHKB,PI4KA,PI4KB,PIGK,PIGX,PJA2,PLCB3,PODNL1,PPT2,PRKAG2,PRKDC,PSKH1,PTGER2,PTK2B,RAB3GAP2,RAB4A,RBM38,RGP1,RGS14,RMND5A,RNF24,RNPEPL1,S100A1,SAMD3,SAPS2,SDR39U1,SLC11A2,SLC41A3,SLCO4C1,SMARCAL1,SMCR7,SPRR4,STARD10,STIM1,TAOK3,TBCD,TCF7,TCFCP2,TEX9,TMEM104,TMEM120A,TMEM161A,TMEM42,TMEM60,TMEM63A,TMEM8,TNFRSF23,TRAF3IP2,TROVE2,TSNAX,TTC15,TUBGCP2,TUBGCP6,UBE4A,UNKL,VAPB,VMN2R56,VPS39,WDFY2,WDR26,WDR83,WDYHV1,WIBG,WIPI2,YPEL2,YWHAQ,ZBTB33,ZDHHC18,ZFP125,ZFP426,ZFP707,ZFP719,ZFP773,ZMYND11
GENE_SYMBOLS	,,,,,,,,,,,,,,,,LINC-PINT,ABCB10,ABTB1,,ACSS2,ANXA7,ARL11,ASH1L,B3GNT2,,BCKDHB,BCL7A,BCS1L,,BTBD19,FAM8A1,CALM1,CAPN1,CASP7,CC2D1A,ODAD1,CCNG1,CFL1,CHD9,CHRNB1,CLCN3,COBLL1,COMMD2,CSTB,CTDSPL2,CTSC,CTSW,CUL3,,CYB5R1,ZFTRAF1,,,,,DMXL2,DUSP7,,EEFSEC,EIF4B,ELOVL5,ENTPD5,FAAH,OTULINL,,PHETA2,HYCC2,FAM174B,EVA1B,FAM53B,,FMO5,FNIP2,FOXO4,,GALNT12,,GLUD1,,,,,,GPBP1L1,GPR132,GRHPR,GYS1,H6PD,HDAC10,HIP1,HS1BP3,HSF4,HSPBAP1,ICOS,IDUA,IKZF5,JMJD4,KAT2B,KIF16B,KLF12,KRT80,AFG1L,LANCL1,LETMD1,MAP4K1,MAPKBP1,MAVS,MED24,MLEC,MLF2,MOB3A,MPRIP,MPV17L,MRI1,MRPL40,MYO18A,NDFIP1,NDUFAF1,NDUFV1,NPRL2,PADI2,PDCD6IP,GATD1,GATB,PFKFB4,PHKB,PI4KA,PI4KB,PIGK,PIGX,PJA2,PLCB3,PODNL1,PPT2,PRKAG2,PRKDC,PSKH1,PTGER2,PTK2B,RAB3GAP2,RAB4A,RBM38,RGP1,RGS14,RMND5A,RNF24,RNPEPL1,S100A1,SAMD3,PPP6R2,SDR39U1,SLC11A2,SLC41A3,SLCO4C1,SMARCAL1,MIEF2,SPRR4,STARD10,STIM1,TAOK3,TBCD,TCF7,,TEX9,TMEM104,TMEM120A,TMEM161A,TMEM42,TMEM60,TMEM63A,PGAP6,,TRAF3IP2,RO60,TSNAX,TRAPPC12,TUBGCP2,TUBGCP6,UBE4A,UNKL,VAPB,,VPS39,WDFY2,WDR26,WDR83,NTAQ1,PYM1,WIPI2,YPEL2,YWHAQ,ZBTB33,ZDHHC18,,,,,,ZMYND11
FOUNDER_NAMES