STANDARD_NAME	GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_UP
SYSTEMATIC_NAME	M5992
COLLECTION	C7:IMMUNESIGDB
MSIGDB_URL	https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_UP
NAMESPACE	HUMAN_GENE_SYMBOL
DESCRIPTION_BRIEF	Genes up-regulated in macrophages treated by IL6 [GeneID=3569] for 100min: wildtype versus SOCS3 [GeneID=9021].
DESCRIPTION_FULL	Effects of SOCS3 on the transcriptional response of bone marrow-derived macrophages to IL-6. Fetal liver cells from SOCS3+/+ or SOCS3-/- embryos were used to reconstitute recipient mice. Donor derived bone marrow from these mice was differentiated to macrophages. Macrophages were either unstimulated, or stimulated for 100 or 400 minutes with 10 ng/ml IL-6.
PMID	12754506
GEOID	GSE411
AUTHORS	Lang R,Pauleau AL,Parganas E,Takahashi Y,Mages J,Ihle JN,Rutschman R,Murray PJ
CONTRIBUTOR	Jernej Godec
CONTRIBUTOR_ORG	Dana-Farber Cancer Institute
EXACT_SOURCE	GSE411_2907_200_UP
FILTERED_BY_SIMILARITY	
EXTERNAL_NAMES_FOR_SIMILAR_TERMS	
EXTERNAL_DETAILS_URL	
SOURCE_MEMBERS	AARSD1,ABHD14A,ABI2,ACADVL,ACER3,ACTR10,ADAM8,ADIPOR1,AK3,ALAD,ALDH18A1,ALPK2,ANAPC13,AP2B1,APIP,ARF4,ARFIP2,ARIH1,ASCC3,ATOH8,ATP5G3,ATP5O,ATP6AP2,ATP6V0C,AURKA,BASP1,BATF3,BRCA1,BUB1,C11orf82,C12orf23,C17orf101,C17orf81,C2orf56,CACNA1E,CACNA1H,CACNB3,CAMK2A,CANX,CAPN5,CASS4,CD2BP2,CD300A,CD300C,CD8A,CDCA5,CDK2AP2,CDK5RAP3,CDKN2B,CEBPB,CELA1,CENPF,CEP192,CHAC1,CHI3L1,CHTF18,CLPTM1,CLTB,CRIP2,CYB5A,CYTIP,DDX50,DDX56,DHFR,DLGAP5,DNA2,DNAJB11,DNAJC1,DNAJC10,DNAJC13,DPAGT1,DYM,ECI2,EDF1,EHD4,EIF2S1,EIF4EBP1,EIF6,ERH,ESPL1,ETFDH,EZH2,F2RL1,FAM117A,FKBP2,FOSB,FOXM1,FOXN2,GCDH,GLRX2,GMPS,GNB4,GNE,GNL3,GOLPH3L,GSTT2,GUK1,HAUS1,HBS1L,HCFC2,HS2ST1,HSPA1B,HSPB6,IFITM2,IFRD2,IGLC7,IMMT,IPO11,IQGAP2,ITGAX,JMJD8,KIAA1826,KIFC1,LAPTM4A,LCORL,LMF2,LRR1,LSR,LTF,MAB21L3,MAN1B1,MCM6,MDH2,MRPL55,MRPS10,MTX2,NAA20,NCAPD2,NCAPH,NDUFB8,NMT1,NSDHL,NUSAP1,P2RY14,PADI4,PAPSS1,PAQR9,PDCL,PELO,PFDN6,PKM2,PLCD1,PLK4,PPM1H,PPP1R10,PRIM1,PRR5,PSMB7,PSMD1,PSMD6,PSMD7,PYCR2,RAB2A,RAB3D,RECQL4,RILPL1,RIOK3,RNASEH2B,RNF187,RNH1,ROPN1L,RPLP0,SDHD,SHB,SHCBP1,SIVA1,SLC11A1,SLC12A4,SLC22A23,SLC38A10,SLC39A4,SLCO4A1,SMPD1,SRGN,TCF19,TF,TGFBI,TIMM17B,TM9SF1,TMCC1,TMEM140,TOMM20,TOR1B,TOR2A,TPI1,TRABD,TRAIP,TRPM2,TSPO,UHRF1,UHRF2,UNC50,UQCRB,VAT1,YARS,ZCCHC18,ZDHHC14,ZFAND3,ZNF473,ZNHIT1
GENE_SYMBOLS	AARSD1,ABHD14A,ABI2,ACADVL,ACER3,ACTR10,ADAM8,ADIPOR1,AK3,ALAD,ALDH18A1,ALPK2,ANAPC13,AP2B1,APIP,ARF4,ARFIP2,ARIH1,ASCC3,ATOH8,ATP5MC3,ATP5PO,ATP6AP2,ATP6V0C,AURKA,BASP1,BATF3,BRCA1,BUB1,DDIAS,TMEM263,OGFOD3,ELP5,NDUFAF7,CACNA1E,CACNA1H,CACNB3,CAMK2A,CANX,CAPN5,CASS4,CD2BP2,CD300A,CD300C,CD8A,CDCA5,CDK2AP2,CDK5RAP3,CDKN2B,CEBPB,CELA1,CENPF,CEP192,CHAC1,CHI3L1,CHTF18,CLPTM1,CLTB,CRIP2,CYB5A,CYTIP,DDX50,DDX56,DHFR,DLGAP5,DNA2,DNAJB11,DNAJC1,DNAJC10,DNAJC13,DPAGT1,DYM,ECI2,EDF1,EHD4,EIF2S1,EIF4EBP1,EIF6,ERH,ESPL1,ETFDH,EZH2,F2RL1,FAM117A,FKBP2,FOSB,FOXM1,FOXN2,GCDH,GLRX2,GMPS,GNB4,GNE,GNL3,GOLPH3L,GSTT2,GUK1,HAUS1,HBS1L,HCFC2,HS2ST1,HSPA1B,HSPB6,IFITM2,IFRD2,IGLC7,IMMT,IPO11,IQGAP2,ITGAX,JMJD8,MSANTD4,KIFC1,LAPTM4A,LCORL,LMF2,LRR1,LSR,LTF,MAB21L3,MAN1B1,MCM6,MDH2,MRPL55,MRPS10,MTX2,NAA20,NCAPD2,NCAPH,NDUFB8,NMT1,NSDHL,NUSAP1,P2RY14,PADI4,PAPSS1,PAQR9,PDCL,PELO,PFDN6,PKM,PLCD1,PLK4,PPM1H,PPP1R10,PRIM1,PRR5,PSMB7,PSMD1,PSMD6,PSMD7,PYCR2,RAB2A,RAB3D,RECQL4,RILPL1,RIOK3,RNASEH2B,RNF187,RNH1,ROPN1L,RPLP0,SDHD,SHB,SHCBP1,SIVA1,SLC11A1,SLC12A4,SLC22A23,SLC38A10,SLC39A4,SLCO4A1,SMPD1,SRGN,TCF19,TF,TGFBI,TIMM17B,TM9SF1,TMCC1,TMEM140,TOMM20,TOR1B,TOR2A,TPI1,TRABD,TRAIP,TRPM2,TSPO,UHRF1,UHRF2,UNC50,UQCRB,VAT1,YARS1,ZCCHC18,ZDHHC14,ZFAND3,ZNF473,ZNHIT1
FOUNDER_NAMES