STANDARD_NAME HOLLEMAN_DAUNORUBICIN_ALL_DN SYSTEMATIC_NAME M2564 COLLECTION C2:CGP MSIGDB_URL https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/HOLLEMAN_DAUNORUBICIN_ALL_DN NAMESPACE AFFY_HG_U133 DESCRIPTION_BRIEF Genes distinguishing daunorubicin [PubChem=30323] resistant and sensitive ALL (B- and T-lineage ALL); here - genes down-regulated in the drug resistant samples. DESCRIPTION_FULL Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percent of patients. However, the cause of treatment failure in the remaining 20 percent of patients is largely unknown. PMID 15295046 GEOID GSE635 AUTHORS Holleman A,Cheok MH,den Boer ML,Yang W,Veerman AJ,Kazemier KM,Pei D,Cheng C,Pui CH,Relling MV,Janka-Schaub GE,Pieters R,Evans WE CONTRIBUTOR Arthur Liberzon CONTRIBUTOR_ORG MSigDB Team EXACT_SOURCE Fig. 12S: R/S < 1 FILTERED_BY_SIMILARITY EXTERNAL_NAMES_FOR_SIMILAR_TERMS EXTERNAL_DETAILS_URL SOURCE_MEMBERS 202777_at,203112_s_at,205070_at,213061_s_at,213264_at,218010_x_at,218438_s_at,222251_s_at GENE_SYMBOLS SHOC2,NELFA,ING3,NTAN1,PCBP2,PPDPF,MED28,GMEB2 FOUNDER_NAMES