STANDARD_NAME HOLLEMAN_PREDNISOLONE_RESISTANCE_ALL_UP SYSTEMATIC_NAME M2558 COLLECTION C2:CGP MSIGDB_URL https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/HOLLEMAN_PREDNISOLONE_RESISTANCE_ALL_UP NAMESPACE AFFY_HG_U133 DESCRIPTION_BRIEF Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive ALL (B- and T-lineage ALL); here - genes up-regulated in the drug resistant samples. DESCRIPTION_FULL Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percent of patients. However, the cause of treatment failure in the remaining 20 percent of patients is largely unknown. PMID 15295046 GEOID GSE635 AUTHORS Holleman A,Cheok MH,den Boer ML,Yang W,Veerman AJ,Kazemier KM,Pei D,Cheng C,Pui CH,Relling MV,Janka-Schaub GE,Pieters R,Evans WE CONTRIBUTOR Arthur Liberzon CONTRIBUTOR_ORG MSigDB Team EXACT_SOURCE Fig. 9S: R/S ratio > 1 FILTERED_BY_SIMILARITY EXTERNAL_NAMES_FOR_SIMILAR_TERMS EXTERNAL_DETAILS_URL SOURCE_MEMBERS 201821_s_at,203274_at,203521_s_at,206865_at,208620_at,208739_x_at,208765_s_at,209675_s_at,209760_at,210053_at,210092_at,212100_s_at,212167_s_at,212180_at,212726_at,213061_s_at,217729_s_at,218381_s_at,218438_s_at,38710_at GENE_SYMBOLS TIMM17A,F8A1,ZNF318,HRK,PCBP1,SUMO2,HNRNPR,HNRNPUL1,TMEM131L,TAF5,MAGOH,POLDIP3,SMARCB1,CRKL,PHF2,NTAN1,TLE5,U2AF2,MED28,OTUB1 FOUNDER_NAMES