STANDARD_NAME	KEGG_PENTOSE_PHOSPHATE_PATHWAY
SYSTEMATIC_NAME	M1386
COLLECTION	C2:CP:KEGG_LEGACY
MSIGDB_URL	https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/KEGG_PENTOSE_PHOSPHATE_PATHWAY
NAMESPACE	Human_NCBI_Gene_ID
DESCRIPTION_BRIEF	Pentose phosphate pathway
DESCRIPTION_FULL	The pentose phosphate pathway is a process of glucose turnover that produces NADPH as reducing equivalents and pentoses as essential parts of nucleotides. There are two different phases in the pathway. One is irreversible oxidative phase in which glucose-6P is converted to ribulose-5P by oxidative decarboxylation, and NADPH is generated. The other is reversible non-oxidative phase in which phosphorylated sugars are interconverted to generate xylulose-5P, ribulose-5P, and ribose-5P. Phosphoribosyl pyrophosphate (PRPP) formed from ribose-5P is an activated compound used in the biosynthesis of histidine and purine/pyrimidine nucleotides. This pathway map also shows the Entner-Doudoroff pathway where 6-P-gluconate is dehydrated and then cleaved into pyruvate and glyceraldehyde-3P.
PMID	
GEOID	
AUTHORS	
CONTRIBUTOR	KEGG
CONTRIBUTOR_ORG	Kyoto Encyclopedia of Genes and Genomes
EXACT_SOURCE	hsa00030
FILTERED_BY_SIMILARITY	
EXTERNAL_NAMES_FOR_SIMILAR_TERMS	
EXTERNAL_DETAILS_URL	http://www.genome.jp/pathway/hsa00030
SOURCE_MEMBERS	2203,221823,226,229,22934,230,2539,25796,2821,51071,5211,5213,5214,5226,5236,55276,5631,5634,6120,64080,6888,7086,729020,8277,84076,8789,9563
GENE_SYMBOLS	FBP1,PRPS1L1,ALDOA,ALDOB,RPIA,ALDOC,G6PD,PGLS,GPI,DERA,PFKL,PFKM,PFKP,PGD,PGM1,PGM2,PRPS1,PRPS2,RPE,RBKS,TALDO1,TKT,RPEL1,TKTL1,TKTL2,FBP2,H6PD
FOUNDER_NAMES