STANDARD_NAME	LANG_MYB_FAMILY_TARGETS
SYSTEMATIC_NAME	M1128
COLLECTION	C2:CGP
MSIGDB_URL	https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/LANG_MYB_FAMILY_TARGETS
NAMESPACE	Mouse_NCBI_Gene_ID
DESCRIPTION_BRIEF	Myb family target genes.
DESCRIPTION_FULL	Hematopoiesis, the process by which mature blood cells arise, is controlled by multiple transcription factors, which act in stage- and lineage-specific complexes. It is a major goal to elucidate the genes regulated by these transcription factors, in order to obtain a full understanding of the process and its malignant counterpart, leukemia. Myb family transcription factors play a central role in hematopoiesis. To identify new Myb family target genes, we have used an inducible dominant-negative protein for a subtraction cloning protocol in a model cell system (FDCP-Mix) with many characteristics of normal hematopoiesis. We present here a novel group of 29 validated Myb family target genes of diverse functions.
PMID	15608679
GEOID	
AUTHORS	Lang G,White JR,Argent-Katwala MJ,Allinson CG,Weston K
CONTRIBUTOR	Arthur Liberzon
CONTRIBUTOR_ORG	MSigDB Team
EXACT_SOURCE	Table 1
FILTERED_BY_SIMILARITY	
EXTERNAL_NAMES_FOR_SIMILAR_TERMS	
EXTERNAL_DETAILS_URL	
SOURCE_MEMBERS	109711,110920,11797,11800,12368,12418,12461,12508,12757,12847,15481,17120,17698,18674,19055,20514,20515,21426,215632,21856,224481,246707,28114,29875,54399,56086,66540,68268,69162
GENE_SYMBOLS	ACTN1,HSPA13,BIRC2,API5,CASP6,CBX4,CCT2,CD53,CLTA,COPA,HSPA8,MAD1L1,MSN,SLC25A3,PPP3CA,SLC1A5,SLC20A1,TFEC,PSD4,TIMM44,TFB1M,EMILIN2,NSUN2,IQGAP1,BET1L,SET,FAM107B,ZDHHC21,SEC31A
FOUNDER_NAMES