STANDARD_NAME MINGUEZ_LIVER_CANCER_VASCULAR_INVASION_DN SYSTEMATIC_NAME M398 COLLECTION C2:CGP MSIGDB_URL https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/MINGUEZ_LIVER_CANCER_VASCULAR_INVASION_DN NAMESPACE Human_NCBI_Gene_ID DESCRIPTION_BRIEF Genes under-expressed in hepatocellular carcinoma (HCC) with vascular invasion. DESCRIPTION_FULL In approximately 70% of patients with hepatocellular carcinoma (HCC) treated by resection or ablation, disease recurs within 5 years. Although gene expression signatures have been associated with outcome, there is no method to predict recurrence based on combined clinical, pathology, and genomic data (from tumor and cirrhotic tissue). We evaluated gene expression signatures associated with outcome in a large cohort of patients with early stage (Barcelona-Clinic Liver Cancer 0/A), single-nodule HCC and heterogeneity of signatures within tumor tissues. PMID 21320499 GEOID GSE20238 AUTHORS Villanueva A,Hoshida Y,Battiston C,Tovar V,Sia D,Alsinet C,Cornella H,Liberzon A,Kobayashi M,Kumada H,Thung SN,Bruix J,Newell P,April C,Fan JB,Roayaie S,Mazzaferro V,Schwartz ME,Llovet JM CONTRIBUTOR Yujin Hoshida CONTRIBUTOR_ORG Broad Institute EXACT_SOURCE Table 2: Signal-to-noise ratio < 0 FILTERED_BY_SIMILARITY EXTERNAL_NAMES_FOR_SIMILAR_TERMS EXTERNAL_DETAILS_URL SOURCE_MEMBERS 10157,10171,10249,10747,10891,127,1576,1807,4143,4638,5053,5105,5295,54407,5444,55089,687,7366,7763,91614,92292 GENE_SYMBOLS AASS,RCL1,GLYAT,MASP2,PPARGC1A,ADH4,CYP3A4,DPYS,MAT1A,MYLK,PAH,PCK1,PIK3R1,SLC38A2,PON1,SLC38A4,KLF9,UGT2B15,ZFAND5,DEPDC7,GLYATL1 FOUNDER_NAMES