STANDARD_NAME	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP
SYSTEMATIC_NAME	M41122
COLLECTION	C7:VAX
MSIGDB_URL	https://www.gsea-msigdb.org/gsea/msigdb/human/geneset/NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP
NAMESPACE	HUMAN_GENE_SYMBOL
DESCRIPTION_BRIEF	Genes up-regulated in plasmacytoid dendritic cell 7d vs 0d in young adults (18-50) after exposure to FluMist , time point 7D
DESCRIPTION_FULL	Here we have used a systems biology approach to study innate and adaptive responses to vaccination against influenza in humans during three consecutive influenza seasons. We studied healthy adults vaccinated with trivalent inactivated influenza vaccine (TIV) or live attenuated influenza vaccine (LAIV). TIV induced higher antibody titers and more plasmablasts than LAIV did. In subjects vaccinated with TIV, early molecular signatures correlated with and could be used to accurately predict later antibody titers in two independent trials. Notably, expression of the kinase CaMKIV at day 3 was inversely correlated with later antibody titers. Vaccination of CaMKIV-deficient mice with TIV induced enhanced antigen-specific antibody titers, which demonstrated an unappreciated role for CaMKIV in the regulation of antibody responses. Thus, systems approaches can be used to predict immunogenicity and provide new mechanistic insights about vaccines.
PMID	21743478
GEOID	
AUTHORS	Nakaya HI,Wrammert J,Lee EK,Racioppi L,Marie-Kunze S,Haining WN,Means AR,Kasturi SP,Khan N,Li GM,McCausland M,Kanchan V,Kokko KE,Li S,Elbein R,Mehta AK,Aderem A,Subbarao K,Ahmed R,Pulendran B
CONTRIBUTOR	HIPC SIGNATURES
CONTRIBUTOR_ORG	NIAID/HIPC SIGNATURES
EXACT_SOURCE	Supplementary Table 2a: LAIV-pDC
FILTERED_BY_SIMILARITY	
EXTERNAL_NAMES_FOR_SIMILAR_TERMS	
EXTERNAL_DETAILS_URL	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140559/bin/NIHMS301940-supplement-3.xlsx
SOURCE_MEMBERS	AACS,ABCB1,ABCB4,ABCC4,ABHD2,ACACA,ACAT1,ACSF2,ACSL3,ACSL4,ACTA2,ACTR6,ADA,ADAM10,ADAM22,ADAM9,ADCK2,ADD1,ADD3,ADI1,ADK,ADNP,ADRB2,ADRBK2,AFF1,AFG3L2,AGA,AGPAT5,AGTPBP1,AIMP2,AJAP1,AK1,AK2,AKAP2,AKT3,ALCAM,ALDH5A1,ALG13,ALG5,AMD1,AMIGO2,AMY1A,AMY1B,AMY1C,AMY2A,AMY2B,ANGEL2,ANKFY1,ANKHD1,ANKHD1-EIF4EBP3,ANKMY2,ANKRD10,ANKRD17,ANKRD49,ANXA2,ANXA4,ANXA7,AP2B1,APAF1,APC,API5,APOBEC3G,APOOL,APPBP2,APPL1,AR,ARAP2,AREG,ARF3,ARF4,ARFGEF2,ARG2,ARHGAP12,ARHGAP15,ARHGAP17,ARHGAP24,ARHGEF7,ARIH1,ARL1,ARL3,ARL8B,ASCC3,ASF1A,ASMTL,ASNS,ASNSD1,ASXL2,ATAD2B,ATF1,ATF2,ATF7,ATG12,ATM,ATP10A,ATP13A3,ATP2A2,ATP2C1,ATP5C1,ATP5SL,ATP6V1A,ATP9B,ATRX,ATXN1,ATXN10,AUTS2,AVL9,AZI2,BAG6,BANK1,BAZ1A,BBS4,BCL11A,BCL2L1,BCL2L11,BEX4,BIN1,BLMH,BMP2K,BMPR2,BRE,BRIX1,BSPRY,BTAF1,BTBD3,BTG1,BTG2,BTK,BUB3,BUD31,BZW1,C10orf137,C10orf26,C10orf88,C11orf21,C11orf24,C11orf57,C11orf95,C12orf43,C12orf52,C14orf1,C14orf118,C14orf169,C16orf80,C17orf62,C17orf85,C18orf25,C19orf2,C19orf42,C1orf107,C1orf112,C1orf50,C1orf63,C1QBP,C20orf103,C21orf59,C2CD5,C2orf28,C6orf162,C7orf25,C7orf26,C7orf28A,C7orf28B,C9orf114,CA8,CALCRL,CAMSAP1,CAND2,CAP1,CAPN7,CAPNS1,CAPZA1,CAPZB,CARD8,CARF,CARS,CAT,CBX1,CCDC47,CCDC59,CCDC86,CCDC90B,CCDC91,CCDC93,CCDC94,CCND2,CCND3,CCNG1,CCNG2,CCNT2,CCR1,CCR2,CCT2,CCT4,CCT6A,CD164,CD55,CDC16,CDK12,CDK13,CDK2AP1,CDK2AP2,CDK5RAP1,CDR2,CDYL,CELF1,CELF2,CENPJ,CEP110,CEP290,CEP350,CEP57,CEP63,CEP68,CETN3,CHD9,CHST11,CHST15,CHTOP,CIAPIN1,CISD1,CITED2,CIZ1,CLCN3,CLIC3,CLIP1,CLK1,CLTA,CMAS,CMKLR1,CMPK1,CMTM6,CNDP2,CNIH,CNOT1,CNOT4,COBLL1,COG2,COG8,COIL,COMT,COPB1,COPS2,COPS6,COPS8,COPZ1,COX11,COX15,COX16,CPD,CREB1,CREBL2,CREBZF,CRELD2,CREM,CRIM1,CSE1L,CSF2RA,CSNK1A1,CSNK1D,CSRP2,CTBP2,CTBS,CTNNA1,CTNS,CTSB,CUEDC1,CUL4A,CUL4B,CUL5,CUTC,CYFIP1,CYFIP2,DAAM1,DAB2,DAD1,DAP3,DAPK1,DARS,DBF4,DCAF13,DCAF7,DCK,DCP2,DCTN3,DDX19A,DDX27,DDX42,DDX6,DECR1,DENND4B,DERA,DERL2,DGCR2,DGKA,DGUOK,DHDDS,DHFR,DIAPH1,DICER1,DIMT1L,DLEU1,DMTF1,DMXL1,DMXL2,DNAJB9,DNAJC10,DNAJC13,DNAJC24,DNAJC8,DNAJC9,DNASE1L3,DNTTIP2,DPP3,DPP8,DPYSL2,DR1,DSCR3,DSG2,DUSP3,DUSP6,DXO,DYNC1H1,DZIP3,E2F5,EAF2,EBNA1BP2,EBP,ECH1,ECHS1,ECPAS,EDEM2,EEA1,EFCAB2,EFHA1,EFHC1,EFR3A,EGLN1,EGR1,EID1,EIF1AX,EIF2B1,EIF2C2,EIF2S1,EIF2S2,EIF3B,EIF3G,EIF3J,EIF3M,EIF5B,ELAVL1,ELF1,ELL3,ELMO2,EML4,ENO1,ENOPH1,ENPP2,ENPP4,ENSA,ENTPD1,ENTPD6,EPHB1,EPM2A,EPRS,EPS15,ERAP1,ERAP2,ERBIN,ERCC1,ERLIN2,ERMAP,ERO1LB,ERP44,ESD,ETNK1,EVI5,EWSR1,EXOC5,EXOSC8,EZH1,F8A1,F8A2,F8A3,FAF1,FAHD2A,FAIM3,FAM105A,FAM117A,FAM134A,FAM13A,FAM175B,FAM178A,FAM208A,FAM3C,FAM45A,FAM48A,FAM49A,FAM65B,FAM82A2,FAM82B,FANCI,FAR2,FASTKD1,FASTKD2,FDFT1,FECH,FEM1B,FEZ2,FGFR2,FHL1,FIBP,FKBP5,FLI1,FLNB,FLOT1,FLOT2,FLT3,FMR1,FNDC3A,FUT4,FYN,GADD45A,GALNT1,GALNT3,GALNT7,GATB,GCOM1,GCSH,GDE1,GDS1,GGH,GK,GLCE,GLMN,GLO1,GLOD4,GLRX,GLRX3,GLS,GLUL,GMFB,GNAI3,GNAL,GNB1,GNL3L,GNPAT,GNS,GOLGA4,GOLPH3,GOSR2,GPBP1L1,GPD1L,GPR107,GPR183,GPX7,GRHPR,GRPEL1,GSPT1,GSPT2,GSTM4,GTF2A2,GTF2H5,GTF3A,GYG1,H2AFV,HADH,HARS,HAUS3,HECTD3,HGSNAT,HIBCH,HIC2,HIP1,HIPK3,HIST1H2AC,HIST1H4H,HMG20A,HMG20B,HMGCR,HMGCS1,HN1L,HNRPDL,HS3ST1,HS3ST3B1,HSBP1,HSDL2,HSF2,HSPA13,HSPA4,HSPA5,HSPD1,HSPH1,HUS1,IARS,IBTK,ICE2,IDI1,IDI2-AS1,IFRD1,IFT52,IFT74,IGFBP7,IGHM,IKBKB,IL13RA1,IL18RAP,IL27RA,IL4R,IL6R,INPP4A,INSIG1,INTS1,INTS6,INTS7,IPO5,IPO7,IPW,IQCE,IQGAP1,IQSEC1,IRF2,ISCA1,ISG20,ITGA4,ITGAV,ITGB3BP,ITPR2,JAK2,KARS,KCNA5,KCNAB1,KCTD12,KCTD20,KDELR2,KDM3B,KDM4A,KDM6A,KIAA1012,KIF1A,KIN,KLHDC10,KLHDC2,KMO,KMT2A,KPNA1,KPNA2,KPNA5,KRBOX4,KRCC1,KRT10,KTN1,KYAT3,LAMC1,LAMP2,LAPTM4B,LARP4B,LCP2,LDLRAD4,LEPROT,LHFPL2,LILRB2,LIMS1,LIN37,LMF1,LONP2,LPCAT3,LPGAT1,LRBA,LRCH3,LRPPRC,LRRC40,LRRC8D,LRRFIP2,LSM1,LSM3,LSM5,LTN1,LUC7L3,LYRM4,M6PR,MACF1,MAD2L1,MAGEH1,MAK16,MALT1,MAN2A2,MANF,MAP1LC3B,MAP3K5,MAP3K7,MAP4K5,MAP7D3,MAPK1,MAPK14,MAPKAPK3,MARCH6,MARCH7,MARS,MAT2A,MATR3,MBD1,MBD4,MBNL1,MBNL2,MCC,MCM3AP-AS1,MCM4,MCUB,MDFIC,MDN1,MEAF6,MED28,MED31,MED7,MEF2A,MEF2C,METAP1,MFN1,MGAT4A,MGAT5,MGMT,MIA3,MICB,MINA,MIOS,MIR22HG,MLEC,MLF1IP,MLX,MMRN1,MOAP1,MON2,MOXD1,MPP1,MPRIP,MPV17,MRFAP1L1,MRPL3,MRPL33,MRPL48,MRPS15,MRPS16,MRPS17,MRPS18B,MRS2,MSH3,MSL2,MSRA,MTDH,MTERFD1,MTF2,MTHFD2,MTM1,MTMR1,MTR,MTRR,MTX2,MUTED,MYCBP,MZB1,N4BP1,N4BP2L2,NADK,NAE1,NAGA,NAPA,NBN,NCBP2,NCF4,NCK2,NCOA6,NDST2,NECAP1,NEK9,NFAT5,NFU1,NFX1,NFYB,NFYC,NIPA2,NIPBL,NOC3L,NOD1,NOL8,NOL9,NOP56,NOTCH4,NPEPPS,NPIPL3,NPM1,NR3C1,NR4A2,NR4A3,NRP1,NSDHL,NSL1,NT5C2,NUBP1,NUDT15,NUDT3,NUMA1,NUP160,NUP210,NUP98,OAS1,OAT,OBFC1,OBSL1,OCRL,ODC1,OPA1,OPN3,OSBPL8,OSBPL9,OSTF1,OTUD4,OXCT1,OXR1,OXSR1,P2RY14,P3H2,P4HA1,PAFAH1B1,PAFAH2,PAIP1,PAIP2B,PAK2,PALM2-AKAP2,PAPOLA,PARP2,PARVB,PAXIP1,PBX3,PBXIP1,PCM1,PCMT1,PDCD10,PDCD2,PDCL3,PDE12,PDE4DIP,PDF,PDHB,PDIA5,PDIA6,PEPD,PEX13,PFKFB2,PGAP2,PGM1,PHKB,PHTF1,PI4KA,PIK3CA,PIP4K2A,PITPNA,PJA2,PKP4,PLA2G16,PLCL2,PLEKHB2,PLIN3,PLK4,PLVAP,PLXNC1,PMP22,PNISR,PNOC,POLM,POLR2M,POLR3C,POP4,POP5,POT1,POU4F1,PPIG,PPP1CC,PPP1R10,PPP1R11,PPP1R12A,PPP1R16B,PPP2CB,PPP2R3C,PPP2R5C,PPP2R5D,PPP2R5E,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP6C,PPPDE1,PPPDE2,PQBP1,PRDM10,PRDM2,PRDX4,PRDX6,PRKACB,PRKAG2,PRKCA,PRKCD,PRKCI,PRKDC,PRNP,PRPF38B,PRPF4,PRPF6,PRPF8,PSEN1,PSMA1,PSMA2,PSMB6,PSMB8,PSMD14,PSMD2,PSMD4,PSMG1,PTBP2,PTBP3,PTEN,PTGER4,PTP4A1,PTP4A3,PTPN11,PTPN22,PUM1,PUM2,PWP1,PYGB,PYROXD1,QKI,R3HCC1,R3HDM1,RAB33B,RAB38,RAB3GAP2,RAB40B,RAB5A,RAB6B,RAB7A,RABGAP1L,RABGGTB,RABL3,RAD17,RAD51AP1,RALBP1,RALGAPA1,RANBP1,RAP1,RAP2C,RAPGEF2,RASA1,RBBP6,RBCK1,RBL2,RBM10,RBM15B,RBM28,RBM41,RBM8A,RBMS1,RCAN1,RCN2,RCOR1,RCOR3,RDH11,RDH14,REST,RET,REXO2,RFK,RFWD3,RGS1,RGS10,RGS2,RGS7,RHOQ,RHOT1,RIMS3,RIT1,RMND5B,RNF11,RNF13,RNF130,RNF139,RNF14,RNF8,ROCK1,RPA2,RPA3,RPAP3,RPE,RPF1,RPL13,RPP38,RPS6KA2,RPS6KA3,RPS6KA4,RQCD1,RRBP1,RRN3,RRP1B,RSAD1,RSL1D1,RUBCN,RUFY3,RUNX1-IT1,RUVBL2,RWDD2B,RXRB,RYR3,S100A10,S100PBP,SAC3D1,SACS,SAE1,SC4MOL,SC5DL,SCD,SCN9A,SCP2,SCUBE3,SCYL2,SCYL3,SDHAF3,SEC22B,SEC23B,SEC24A,SEC31A,SEC62,SECISBP2L,SEL1L,SEL1L3,SENP3,SENP6,SEPT11,SERINC3,SERINC4,SERP1,SESN1,SETD6,SETX,SF4,SFRS17A,SFRS6,SFRS8,SH3BGR,SH3BGRL,SH3BP4,SH3GLB1,SHMT2,SHQ1,SIDT1,SIDT2,SIK1,SIP1,SLC11A2,SLC15A2,SLC16A7,SLC18A2,SLC1A4,SLC24A1,SLC25A32,SLC25A46,SLC30A9,SLC33A1,SLC35A2,SLC35A3,SLC35D1,SLC38A1,SLC39A6,SLC43A3,SLC4A3,SLC4A7,SLC5A3,SLC7A1,SLC7A6,SLC9A6,SLMO2,SMAD3,SMAP1,SMARCA5,SMARCAL1,SMARCC1,SMG1,SMURF2,SMYD2,SNAP23,SNAPC3,SNAPC5,SNCA,SNRNP200,SNX13,SOD2,SOLH,SOS2,SP110,SP4,SPAG9,SPAST,SPCS2,SPG7,SPIN2A,SPIN2B,SPOP,SPTBN1,SR140,SRPK2,SRPRB,SSX4,SSX4B,ST13,ST3GAL1,ST3GAL6,ST6GALNAC4,STAM2,STAMBP,STAT6,STIM1,STK26,STX18,STX6,SUMO1,SUN1,SUPT3H,SUZ12,SYK,SYNE2,TACC1,TAF12,TAF1B,TAF4,TANK,TAX1BP3,TBC1,TBC1D4,TBC1D5,TBCC,TBCCD1,TBL2,TBPL1,TCF3,TCF4,TCL1A,TCP1,TDG,TDP1,TDRD3,TEX10,TFCP2,THAP1,THBD,THOC2,THOC7,THUMPD1,TIA1,TIMELESS,TIMM17A,TLR6,TLR7,TM2D1,TMBIM6,TMCO1,TMCO6,TMED10,TMED5,TMED7,TMEM131,TMEM14A,TMEM184C,TMEM185B,TMEM33,TMEM38B,TMEM39A,TMEM50A,TMEM59,TMEM70,TMPO,TMUB2,TMX4,TNPO1,TOB2,TOP3A,TOPBP1,TOR1A,TOR1B,TPD52,TPM4,TPRKB,TRAK1,TRAM1,TRAM2,TRAPPC10,TRDMT1,TRIM14,TRIM27,TRIM33,TRIM38,TRIP11,TRMT61B,TROVE2,TRPS1,TRPV1,TSC1,TSC22D1,TSC22D3,TSNAX,TSPAN31,TSR1,TTC13,TTC3,TTC35,TTC37,TTF1,TUBB,TUBB2C,TUBB3,TUBGCP4,TWF1,TXNDC3,TXNDC5,U2AF2,UBA2,UBA3,UBAP1,UBAP2L,UBE2B,UBE2D3,UBE2E3,UBE2J1,UBE2L3,UBE3A,UBE4A,UBE4B,UBFD1,UBL3,UBR2,UBR5,UBR7,UBTF,UCHL3,UCP2,UEVLD,UPF2,UPF3A,UQCR10,UQCRB,USP1,USP15,USP4,USP6,USP9X,UTP11,VAMP1,VCL,VPS11,VPS41,VPS45,VSNL1,WAC,WAPAL,WASF1,WASHC2A,WASHC2C,WASHC3,WASHC4,WBP11,WBP4,WDR1,WDR3,WDR37,WDR47,WDR59,WDR70,WIPF2,WIPI1,WSB1,WSB2,XPO1,XRCC4,XRCC5,YAF2,YKT6,YWHAE,YWHAQ,ZBTB10,ZBTB25,ZBTB33,ZC3H14,ZC3H15,ZCCHC24,ZFP36L2,ZMYM2,ZMYM4,ZMYND11,ZMYND8,ZNF106,ZNF117,ZNF124,ZNF131,ZNF148,ZNF195,ZNF202,ZNF207,ZNF224,ZNF226,ZNF238,ZNF277,ZNF329,ZNF337,ZNF354A,ZNF544,ZNF609,ZNF7,ZNF713,ZNF814,ZNF83,ZNHIT6
GENE_SYMBOLS	AACS,ABCB1,ABCB4,ABCC4,ABHD2,ACACA,ACAT1,ACSF2,ACSL3,ACSL4,ACTA2,ACTR6,ADA,ADAM10,ADAM22,ADAM9,ADCK2,ADD1,ADD3,ADI1,ADK,ADNP,ADRB2,GRK3,AFF1,AFG3L2,AGA,AGPAT5,AGTPBP1,AIMP2,AJAP1,AK1,AK2,,AKT3,ALCAM,ALDH5A1,ALG13,ALG5,AMD1,AMIGO2,AMY1A,AMY1B,AMY1C,AMY2A,AMY2B,ANGEL2,ANKFY1,ANKHD1,ANKHD1-EIF4EBP3,ANKMY2,ANKRD10,ANKRD17,ANKRD49,ANXA2,ANXA4,ANXA7,AP2B1,APAF1,APC,API5,APOBEC3G,APOOL,APPBP2,APPL1,AR,ARAP2,AREG,ARF3,ARF4,ARFGEF2,ARG2,ARHGAP12,ARHGAP15,ARHGAP17,ARHGAP24,ARHGEF7,ARIH1,ARL1,ARL3,ARL8B,ASCC3,ASF1A,ASMTL,ASNS,ASNSD1,ASXL2,ATAD2B,ATF1,ATF2,ATF7,ATG12,ATM,ATP10A,ATP13A3,ATP2A2,ATP2C1,ATP5F1C,DMAC2,ATP6V1A,ATP9B,ATRX,ATXN1,ATXN10,AUTS2,AVL9,AZI2,BAG6,BANK1,BAZ1A,BBS4,BCL11A,BCL2L1,BCL2L11,BEX4,BIN1,BLMH,BMP2K,BMPR2,BABAM2,BRIX1,BSPRY,BTAF1,BTBD3,BTG1,BTG2,BTK,BUB3,BUD31,BZW1,EDRF1,WBP1L,C10orf88,C11orf21,C11orf24,NKAPD1,ZFTA,C12orf43,RITA1,ERG28,GPATCH2L,RIOX1,CFAP20,CYBC1,NCBP3,ARK2N,URI1,SMIM7,C1QBP,UTP25,FIRRM,C1orf50,RSRP1,LAMP5,CFAP298,C2CD5,ATRAID,SMIM8,C7orf25,INTS15,CCZ1,CCZ1B,SPOUT1,CA8,CALCRL,CAMSAP1,CAND2,CAP1,CAPN7,CAPNS1,CAPZA1,CAPZB,CARD8,CARF,CARS1,CAT,CBX1,CCDC47,CCDC59,CCDC86,CCDC90B,CCDC91,CCDC93,YJU2,CCND2,CCND3,CCNG1,CCNG2,CCNT2,CCR1,CCR2,CCT2,CCT4,CCT6A,CD164,CD55,CDC16,CDK12,CDK13,CDK2AP1,CDK2AP2,CDK5RAP1,CDR2,CDYL,CELF1,CELF2,CPAP,CNTRL,CEP290,CEP350,CEP57,CEP63,CEP68,CETN3,CHD9,CHST11,CHST15,CHTOP,CIAPIN1,CISD1,CITED2,CIZ1,CLCN3,CLIC3,CLIP1,CLK1,CLTA,CMAS,CMKLR1,CMPK1,CMTM6,CNDP2,CNIH1,CNOT1,CNOT4,COBLL1,COG2,COG8,COIL,COMT,COPB1,COPS2,COPS6,COPS8,COPZ1,COX11,COX15,COX16,CPD,CREB1,CREBL2,CREBZF,CRELD2,CREM,CRIM1,CSE1L,CSF2RA,CSNK1A1,CSNK1D,CSRP2,CTBP2,CTBS,CTNNA1,CTNS,CTSB,CUEDC1,CUL4A,CUL4B,CUL5,CUTC,CYFIP1,CYFIP2,DAAM1,DAB2,DAD1,DAP3,DAPK1,DARS1,DBF4,DCAF13,DCAF7,DCK,DCP2,DCTN3,DDX19A,DDX27,DDX42,DDX6,DECR1,DENND4B,DERA,DERL2,DGCR2,DGKA,DGUOK,DHDDS,DHFR,DIAPH1,DICER1,DIMT1,DLEU1,DMTF1,DMXL1,DMXL2,DNAJB9,DNAJC10,DNAJC13,DNAJC24,DNAJC8,DNAJC9,DNASE1L3,DNTTIP2,DPP3,DPP8,DPYSL2,DR1,VPS26C,DSG2,DUSP3,DUSP6,DXO,DYNC1H1,DZIP3,E2F5,EAF2,EBNA1BP2,EBP,ECH1,ECHS1,ECPAS,EDEM2,EEA1,EFCAB2,MICU2,EFHC1,EFR3A,EGLN1,EGR1,EID1,EIF1AX,EIF2B1,AGO2,EIF2S1,EIF2S2,EIF3B,EIF3G,EIF3J,EIF3M,EIF5B,ELAVL1,ELF1,ELL3,ELMO2,EML4,ENO1,ENOPH1,ENPP2,ENPP4,ENSA,ENTPD1,ENTPD6,EPHB1,EPM2A,EPRS1,EPS15,ERAP1,ERAP2,ERBIN,ERCC1,ERLIN2,ERMAP,ERO1B,ERP44,ESD,ETNK1,EVI5,EWSR1,EXOC5,EXOSC8,EZH1,F8A1,F8A2,F8A3,FAF1,FAHD2A,FCMR,OTULINL,FAM117A,RETREG2,FAM13A,ABRAXAS2,SLF2,TASOR,FAM3C,DENND10,SUPT20H,CYRIA,RIPOR2,RMDN3,RMDN1,FANCI,FAR2,FASTKD1,FASTKD2,FDFT1,FECH,FEM1B,FEZ2,FGFR2,FHL1,FIBP,FKBP5,FLI1,FLNB,FLOT1,FLOT2,FLT3,FMR1,FNDC3A,FUT4,FYN,GADD45A,GALNT1,GALNT3,GALNT7,GATB,GCOM1,GCSH,GDE1,,GGH,GK,GLCE,GLMN,GLO1,GLOD4,GLRX,GLRX3,GLS,GLUL,GMFB,GNAI3,GNAL,GNB1,GNL3L,GNPAT,GNS,GOLGA4,GOLPH3,GOSR2,GPBP1L1,GPD1L,GPR107,GPR183,GPX7,GRHPR,GRPEL1,GSPT1,GSPT2,GSTM4,GTF2A2,GTF2H5,GTF3A,GYG1,H2AZ2,HADH,HARS1,HAUS3,HECTD3,HGSNAT,HIBCH,HIC2,HIP1,HIPK3,H2AC6,H4C8,HMG20A,HMG20B,HMGCR,HMGCS1,JPT2,HNRNPDL,HS3ST1,HS3ST3B1,HSBP1,HSDL2,HSF2,HSPA13,HSPA4,HSPA5,HSPD1,HSPH1,HUS1,IARS1,IBTK,ICE2,IDI1,IDI2-AS1,IFRD1,IFT52,IFT74,IGFBP7,IGHM,IKBKB,IL13RA1,IL18RAP,IL27RA,IL4R,IL6R,INPP4A,INSIG1,INTS1,INTS6,INTS7,IPO5,IPO7,,IQCE,IQGAP1,IQSEC1,IRF2,ISCA1,ISG20,ITGA4,ITGAV,ITGB3BP,ITPR2,JAK2,KARS1,KCNA5,KCNAB1,KCTD12,KCTD20,KDELR2,KDM3B,KDM4A,KDM6A,TRAPPC8,KIF1A,KIN,KLHDC10,KLHDC2,KMO,KMT2A,KPNA1,KPNA2,KPNA5,KRBOX4,KRCC1,KRT10,KTN1,KYAT3,LAMC1,LAMP2,LAPTM4B,LARP4B,LCP2,LDLRAD4,LEPROT,LHFPL2,LILRB2,LIMS1,LIN37,LMF1,LONP2,LPCAT3,LPGAT1,LRBA,LRCH3,LRPPRC,LRRC40,LRRC8D,LRRFIP2,LSM1,LSM3,LSM5,LTN1,LUC7L3,LYRM4,M6PR,MACF1,MAD2L1,MAGEH1,MAK16,MALT1,MAN2A2,MANF,MAP1LC3B,MAP3K5,MAP3K7,MAP4K5,MAP7D3,MAPK1,MAPK14,MAPKAPK3,MARCHF6,MARCHF7,MARS1,MAT2A,MATR3,MBD1,MBD4,MBNL1,MBNL2,MCC,MCM3AP-AS1,MCM4,MCUB,MDFIC,MDN1,MEAF6,MED28,MED31,MED7,MEF2A,MEF2C,METAP1,MFN1,MGAT4A,MGAT5,MGMT,MIA3,MICB,RIOX2,MIOS,MIR22HG,MLEC,CENPU,MLX,MMRN1,MOAP1,MON2,MOXD1,MPP1,MPRIP,MPV17,MRFAP1L1,MRPL3,MRPL33,MRPL48,MRPS15,MRPS16,MRPS17,MRPS18B,MRS2,MSH3,MSL2,MSRA,MTDH,MTERF3,MTF2,MTHFD2,MTM1,MTMR1,MTR,MTRR,MTX2,BLOC1S5,MYCBP,MZB1,N4BP1,N4BP2L2,NADK,NAE1,NAGA,NAPA,NBN,NCBP2,NCF4,NCK2,NCOA6,NDST2,NECAP1,NEK9,NFAT5,NFU1,NFX1,NFYB,NFYC,NIPA2,NIPBL,NOC3L,NOD1,NOL8,NOL9,NOP56,NOTCH4,NPEPPS,NPIPB3,NPM1,NR3C1,NR4A2,NR4A3,NRP1,NSDHL,NSL1,NT5C2,NUBP1,NUDT15,NUDT3,NUMA1,NUP160,NUP210,NUP98,OAS1,OAT,STN1,OBSL1,OCRL,ODC1,OPA1,OPN3,OSBPL8,OSBPL9,OSTF1,OTUD4,OXCT1,OXR1,OXSR1,P2RY14,P3H2,P4HA1,PAFAH1B1,PAFAH2,PAIP1,PAIP2B,PAK2,PALM2AKAP2,PAPOLA,PARP2,PARVB,PAXIP1,PBX3,PBXIP1,PCM1,PCMT1,PDCD10,PDCD2,PDCL3,PDE12,PDE4DIP,PDF,PDHB,PDIA5,PDIA6,PEPD,PEX13,PFKFB2,PGAP2,PGM1,PHKB,PHTF1,PI4KA,PIK3CA,PIP4K2A,PITPNA,PJA2,PKP4,PLAAT3,PLCL2,PLEKHB2,PLIN3,PLK4,PLVAP,PLXNC1,PMP22,PNISR,PNOC,POLM,POLR2M,POLR3C,POP4,POP5,POT1,POU4F1,PPIG,PPP1CC,PPP1R10,PPP1R11,PPP1R12A,PPP1R16B,PPP2CB,PPP2R3C,PPP2R5C,PPP2R5D,PPP2R5E,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP6C,DESI2,DESI1,PQBP1,PRDM10,PRDM2,PRDX4,PRDX6,PRKACB,PRKAG2,PRKCA,PRKCD,PRKCI,PRKDC,PRNP,PRPF38B,PRPF4,PRPF6,PRPF8,PSEN1,PSMA1,PSMA2,PSMB6,PSMB8,PSMD14,PSMD2,PSMD4,PSMG1,PTBP2,PTBP3,PTEN,PTGER4,PTP4A1,PTP4A3,PTPN11,PTPN22,PUM1,PUM2,PWP1,PYGB,PYROXD1,QKI,R3HCC1,R3HDM1,RAB33B,RAB38,RAB3GAP2,RAB40B,RAB5A,RAB6B,RAB7A,RABGAP1L,RABGGTB,RABL3,RAD17,RAD51AP1,RALBP1,RALGAPA1,RANBP1,TERF2IP,RAP2C,RAPGEF2,RASA1,RBBP6,RBCK1,RBL2,RBM10,RBM15B,RBM28,RBM41,RBM8A,RBMS1,RCAN1,RCN2,RCOR1,RCOR3,RDH11,RDH14,REST,RET,REXO2,RFK,RFWD3,RGS1,RGS10,RGS2,RGS7,RHOQ,RHOT1,RIMS3,RIT1,RMND5B,RNF11,RNF13,RNF130,RNF139,RNF14,RNF8,ROCK1,RPA2,RPA3,RPAP3,RPE,RPF1,RPL13,RPP38,RPS6KA2,RPS6KA3,RPS6KA4,CNOT9,RRBP1,RRN3,RRP1B,RSAD1,RSL1D1,RUBCN,RUFY3,,RUVBL2,RWDD2B,RXRB,RYR3,S100A10,S100PBP,SAC3D1,SACS,SAE1,MSMO1,SC5D,SCD,SCN9A,SCP2,SCUBE3,SCYL2,SCYL3,SDHAF3,SEC22B,SEC23B,SEC24A,SEC31A,SEC62,SECISBP2L,SEL1L,SEL1L3,SENP3,SENP6,SEPTIN11,SERINC3,SERINC4,SERP1,SESN1,SETD6,SETX,SUGP1,AKAP17A,SRSF6,SFSWAP,SH3BGR,SH3BGRL,SH3BP4,SH3GLB1,SHMT2,SHQ1,SIDT1,SIDT2,SIK1,GEMIN2,SLC11A2,SLC15A2,SLC16A7,SLC18A2,SLC1A4,SLC24A1,SLC25A32,SLC25A46,SLC30A9,SLC33A1,SLC35A2,SLC35A3,SLC35D1,SLC38A1,SLC39A6,SLC43A3,SLC4A3,SLC4A7,SLC5A3,SLC7A1,SLC7A6,SLC9A6,PRELID3B,SMAD3,SMAP1,SMARCA5,SMARCAL1,SMARCC1,SMG1,SMURF2,SMYD2,SNAP23,SNAPC3,SNAPC5,SNCA,SNRNP200,SNX13,SOD2,CAPN15,SOS2,SP110,SP4,SPAG9,SPAST,SPCS2,SPG7,SPIN2A,SPIN2B,SPOP,SPTBN1,U2SURP,SRPK2,SRPRB,SSX4,SSX4B,ST13,ST3GAL1,ST3GAL6,ST6GALNAC4,STAM2,STAMBP,STAT6,STIM1,STK26,STX18,STX6,SUMO1,SUN1,SUPT3H,SUZ12,SYK,SYNE2,TACC1,TAF12,TAF1B,TAF4,TANK,TAX1BP3,TBC1D1,TBC1D4,TBC1D5,TBCC,TBCCD1,TBL2,TBPL1,TCF3,TCF4,TCL1A,TCP1,TDG,TDP1,TDRD3,TEX10,TFCP2,THAP1,THBD,THOC2,THOC7,THUMPD1,TIA1,TIMELESS,TIMM17A,TLR6,TLR7,TM2D1,TMBIM6,TMCO1,TMCO6,TMED10,TMED5,TMED7,TMEM131,TMEM14A,TMEM184C,TMEM185B,TMEM33,TMEM38B,TMEM39A,TMEM50A,TMEM59,TMEM70,TMPO,TMUB2,TMX4,TNPO1,TOB2,TOP3A,TOPBP1,TOR1A,TOR1B,TPD52,TPM4,TPRKB,TRAK1,TRAM1,TRAM2,TRAPPC10,TRDMT1,TRIM14,TRIM27,TRIM33,TRIM38,TRIP11,TRMT61B,RO60,TRPS1,TRPV1,TSC1,TSC22D1,TSC22D3,TSNAX,TSPAN31,TSR1,TTC13,TTC3,EMC2,SKIC3,TTF1,TUBB,TUBB4B,TUBB3,TUBGCP4,TWF1,NME8,TXNDC5,U2AF2,UBA2,UBA3,UBAP1,UBAP2L,UBE2B,UBE2D3,UBE2E3,UBE2J1,UBE2L3,UBE3A,UBE4A,UBE4B,UBFD1,UBL3,UBR2,UBR5,UBR7,UBTF,UCHL3,UCP2,UEVLD,UPF2,UPF3A,UQCR10,UQCRB,USP1,USP15,USP4,USP6,USP9X,UTP11,VAMP1,VCL,VPS11,VPS41,VPS45,VSNL1,WAC,WAPL,WASF1,WASHC2A,WASHC2C,WASHC3,WASHC4,WBP11,WBP4,WDR1,WDR3,WDR37,WDR47,WDR59,WDR70,WIPF2,WIPI1,WSB1,WSB2,XPO1,XRCC4,XRCC5,YAF2,YKT6,YWHAE,YWHAQ,ZBTB10,ZBTB25,ZBTB33,ZC3H14,ZC3H15,ZCCHC24,ZFP36L2,ZMYM2,ZMYM4,ZMYND11,ZMYND8,ZNF106,ZNF117,ZNF124,ZNF131,ZNF148,ZNF195,ZNF202,ZNF207,ZNF224,ZNF226,ZBTB18,ZNF277,ZNF329,ZNF337,ZNF354A,ZNF544,ZNF609,ZNF7,ZNF713,ZNF814,ZNF83,ZNHIT6
FOUNDER_NAMES