Human Gene Set: BLANCO_MELO_COVID19_SARS_COV_2
      _INFECTION_A594_ACE2_EXPRESSING_CELLS
      _RUXOLITINIB_DN


Standard name BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_ACE2_EXPRESSING_CELLS_RUXOLITINIB_DN
Systematic name M34019
Brief description Genes down-regulated in SARS-CoV-2 infection with Ruxolitinib (ACE2 expressing A549 cells, MOI: 2, 24hpi)
Full description or abstract Analysis of the transcriptional response to SARS-CoV-2 compared with other respiratory viruses, including MERS-CoV, SARS-CoV-1 (SARS), human parainfluenza virus 3 (HPIV3), respiratory syncytial virus (RSV), and IAV.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 32416070   Authors: Blanco-Melo D,Nilsson-Payant BE,Liu WC,Uhl S,Hoagland D,Møller R,Jordan TX,Oishi K,Panis M,Sachs D,Wang TT,Schwartz RE,Lim JK,Albrecht RA,tenOever BR
Exact source Table S1. Differential Gene Expression Analysis of Respiratory Virus Infections in Cell Lines, Related to Figure 1. log2(FC)<-2, padj<0.05
Related gene sets (show 29 additional gene sets from the source publication)

(show 22 gene sets from the same authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Anthony Castanza (MSigDB Team)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 76 genes
Gene families ? Categorize these 76 genes by gene family
Show members (show 76 source identifiers mapped to 76 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.