Human Gene Set: BLANCO_MELO_COVID19_SARS_COV_2_POS_PATIENT_LUNG_TISSUE_DN


Standard name BLANCO_MELO_COVID19_SARS_COV_2_POS_PATIENT_LUNG_TISSUE_DN
Systematic name M34029
Brief description Genes strongly down-regulated (og2(FC)<-3.58, padj<0.05) in post mortem lung tissue from COVID-19 patients vs uninfected biopsy.
Full description or abstract Transcriptional profiling of post-mortem lung samples from COVID-19-positive patients (N=2) compared with biopsied healthy lung tissue from uninfected individuals.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 32416070   Authors: Blanco-Melo D,Nilsson-Payant BE,Liu WC,Uhl S,Hoagland D,Møller R,Jordan TX,Oishi K,Panis M,Sachs D,Wang TT,Schwartz RE,Lim JK,Albrecht RA,tenOever BR
Exact source Table S4. Differential Gene Expression Analysis of COVID-19 Patients, Related to Figure 4. log2(FC)<-3.58, padj<0.05
Related gene sets (show 29 additional gene sets from the source publication)

(show 22 gene sets from the same authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Anthony Castanza (MSigDB Team)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 175 genes
Gene families ? Categorize these 175 genes by gene family
Show members (show 175 source identifiers mapped to 175 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.