Human Gene Set: BRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS
Standard name
BRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS
Systematic name
M9884
Brief description
Genes for which mutations result in developmental defects in the great vessels formation and valvulogenesis, a major class of congenital heart disease.
Full description or abstract
Congenital heart disease is the leading cause of infant morbidity in the Western world, but only in the past ten years has its aetiology been understood. Recent studies have uncovered the genetic basis for some common forms of the disease and provide new insight into how the heart develops and how dysregulation of heart development leads to disease.
Collection
C2: Curated CGP: Chemical and Genetic Perturbations
