Human Gene Set: CARRILLOREIXACH_14Q32OVEREXPRESSION_IN_HEPATOBLASTOMA


Standard name CARRILLOREIXACH_14Q32OVEREXPRESSION_IN_HEPATOBLASTOMA
Systematic name M45035
Brief description Genes enriched in locus DLK1-DIO3 at 14q32 in hepatoblastoma (HB) as compared with non-tumor (NT) adjacent tissue assessed by Human Transcriptome Array (HTA).
Full description or abstract Background & Aims: Hepatoblastoma (HB) is a rare disease. Nevertheless, it is the predominant pediatric liver cancer, with limited therapeutic options for patients with aggressive tumors. Herein, we aimed to uncover the mechanisms of HB pathobiology and to identify new biomarkers and therapeutic targets in a move towards precision medicine for patients with advanced HB.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 32240714   Authors: Carrillo-Reixach J,Torrens L,Simon-Coma M,Royo L,Domingo-Sàbat M,Abril-Fornaguera J,Akers N,Sala M,Ragull S,Arnal M,Villalmanzo N,Cairo S,Villanueva A,Kappler R,Garrido M,Guerra L,Sábado C,Guillén G,Mallo M,Piñeyro D,Vázquez-Vitali M,Kuchuk O,Mateos ME,Ramírez G,Santamaría ML,Mozo Y,Soriano A,Grotzer M,Branchereau S,de Andoin NG,López-Ibor B,López-Almaraz R,Salinas JA,Torres B,Hernández F,Uriz JJ,Fabre M,Blanco J,Paris C,Baj?iová V,Laureys G,Masnou H,Clos A,Belendez C,Guettier C,Sumoy L,Planas R,Jordà M,Nonell L,Czauderna P,Morland B,Sia D,Losic B,Buendia MA,Sarrias MR,Llovet JM,Armengol C
Exact source Supplementary Table 4; Enriched genes in HB
Related gene sets (show 6 additional gene sets from the source publication)

(show 43 gene sets from the same authors)
External links https://www.sciencedirect.com/science/article/pii/S0168827820301872?via%3Dihub
Filtered by similarity ?
Organism Homo sapiens
Contributed by Carolina Armengol (Germans Trias i Pujol Research Institute (IGTP))
Source platform AFFY_HTA_2.0
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 49 genes
Gene families ? Categorize these 49 genes by gene family
Show members (show 96 members mapped to 49 genes)
Version history 2022.1.Hs: First Introduced.

See MSigDB license terms here. Please note that certain gene sets have special access terms.