Human Gene Set: FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS


Standard name FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS
Systematic name M61
Brief description Genes directly bound and regulated by TP53[GeneID=7157].
Full description or abstract Genes identified as transcriptionally activated by p53 in at least 5 out of 20 genome-wide p53 gene expression profiles and identified as bound by p53 within 2.5kb of the TSS in at least 4 out of 15 genome-wide p53 binding profiles.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 27280975   Authors: Fischer M,Grossmann P,Padi M,DeCaprio JA
Exact source Table S3
Related gene sets (show 3 additional gene sets from the source publication)

(show 2 gene sets from any of these authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Martin Fischer (Dana-Farber Cancer Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 311 genes
Gene families ? Categorize these 311 genes by gene family
Show members (show 311 source identifiers mapped to 311 genes)
Version history 6.1: First introduced


Creative Commons Attribution 4.0 International License (CC-BY-4.0)

The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology, and Regents of the University of California, subject to the terms and conditions of the Creative Commons Attribution 4.0 International License.

See the full MSigDB license terms here.