Human Gene Set: GILMORE_CORE_NFKB_PATHWAY


Standard name GILMORE_CORE_NFKB_PATHWAY
Systematic name M8804
Brief description Genes encoding the NF-kB core signaling proteins.
Full description or abstract This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-kappaB). It provides an overview of the discovery and current status of NF-kappaB as a research topic. Described are the structures, activities and regulation of the proteins in the NF-kappaB family of transcription factors. NF-kappaB signaling is primarily regulated by inhibitor kappaB (IkappaB) proteins and the IkappaB kinase complex through two major pathways: the canonical and non-canonical NF-kappaB pathways. The organization and focus of articles included in the following reviews are described, as well as likely future areas of research interest on NF-kappaB.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 17072321   Authors: Gilmore TD
Exact source Table 1: Human
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Source species Homo sapiens
Contributed by Arthur Liberzon (MSigDB Team)
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 3.0: First introduced

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