Human Gene Set: GOBP_APOPTOTIC_DNA_FRAGMENTATION
For the Mouse gene set with the same name, see GOBP_APOPTOTIC_DNA_FRAGMENTATION
Standard name
GOBP_APOPTOTIC_DNA_FRAGMENTATION
Systematic name
M15701
Brief description
The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments. [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976, PMID:15723341, PMID:23379520]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0006309
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0006309
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 18 genes
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18 genes by gene family
Show members
(show 18 source identifiers mapped to 18 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
1149
1149
CIDEA
cell death inducing DFFA like effector a [...
140628
140628
GATA5
GATA binding protein 5 [Source:HGNC Symbol...
1676
1676
DFFA
DNA fragmentation factor subunit alpha [So...
1677
1677
DFFB
DNA fragmentation factor subunit beta [Sou...
1776
1776
DNASE1L3
deoxyribonuclease 1L3 [Source:HGNC Symbol;...
1777
1777
DNASE2
deoxyribonuclease 2, lysosomal [Source:HGN...
2021
2021
ENDOG
endonuclease G [Source:HGNC Symbol;Acc:HGN...
23405
23405
DICER1
dicer 1, ribonuclease III [Source:HGNC Sym...
27443
27443
CECR2
CECR2 histone acetyl-lysine reader [Source...
317
317
APAF1
apoptotic peptidase activating factor 1 [S...
3297
3297
HSF1
heat shock transcription factor 1 [Source:...
3569
3569
IL6
interleukin 6 [Source:HGNC Symbol;Acc:HGNC...
51542
51542
VPS54
VPS54 subunit of GARP complex [Source:HGNC...
581
581
BAX
BCL2 associated X, apoptosis regulator [So...
58511
58511
DNASE2B
deoxyribonuclease 2 beta [Source:HGNC Symb...
64802
64802
NMNAT1
nicotinamide nucleotide adenylyltransferas...
668
668
FOXL2
forkhead box L2 [Source:HGNC Symbol;Acc:HG...
9941
9941
EXOG
exo/endonuclease G [Source:HGNC Symbol;Acc...
Version history
2025.1.Hs: Updated to GO Release 2025-03-16.
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