Human Gene Set: GOBP_CANONICAL_WNT_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT

For the Mouse gene set with the same name, see GOBP_CANONICAL_WNT_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT

Standard name

GOBP_CANONICAL_WNT_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT

Systematic name

M24276

Brief description

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [GOC:mtg_heart]

Full description or abstract

Collection

C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process

Source publication

Exact source

GO:0061316

Related gene sets

External links

http://amigo.geneontology.org/amigo/term/GO:0061316

Filtered by similarity ?

Source species

Homo sapiens