Human Gene Set: GOBP_DOUBLE_STRAND_BREAK_REPAIR_VIA_SYNTHESIS_DEPENDENT_STRAND_ANNEALING

For the Mouse gene set with the same name, see GOBP_DOUBLE_STRAND_BREAK_REPAIR_VIA_SYNTHESIS_DEPENDENT_STRAND_ANNEALING

Standard name

GOBP_DOUBLE_STRAND_BREAK_REPAIR_VIA_SYNTHESIS_DEPENDENT_STRAND_ANNEALING

Systematic name

M23674

Brief description

SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break. [PMID:10357855]

Full description or abstract

Collection

C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process

Source publication

Exact source

GO:0045003

Related gene sets

External links

http://amigo.geneontology.org/amigo/term/GO:0045003

Filtered by similarity ?

Source species

Homo sapiens