Human Gene Set: GOBP_ERROR_FREE_TRANSLESION_SYNTHESIS
Standard name
GOBP_ERROR_FREE_TRANSLESION_SYNTHESIS
Systematic name
M12348
Brief description
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level. [GOC:elh]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
