Human Gene Set: GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY

For the Mouse gene set with the same name, see GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY

Standard name GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY
Systematic name M2280
Brief description The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0007186
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0007186
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
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