Human Gene Set: GOBP_PYROPTOTIC_INFLAMMATORY_RESPONSE

For the Mouse gene set with the same name, see GOBP_PYROPTOTIC_INFLAMMATORY_RESPONSE

Standard name GOBP_PYROPTOTIC_INFLAMMATORY_RESPONSE
Systematic name M24370
Brief description A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death. [PMID:18846107, PMID:21760595, PMID:33883744]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0070269
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0070269
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Version history 2025.1.Hs: Renamed from GOBP_PYROPTOSIS. Updated to GO Release 2025-03-16.

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