Human Gene Set: GOBP_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE_TRANSLOCATION

For the Mouse gene set with the same name, see GOBP_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE_TRANSLOCATION

Standard name

GOBP_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE_TRANSLOCATION

Systematic name

M22442

Brief description

The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen. [ISBN:0716731363]

Full description or abstract

Collection

C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process

Source publication

Exact source

GO:0006616

Related gene sets

External links

http://amigo.geneontology.org/amigo/term/GO:0006616

Filtered by similarity ?

Source species

Homo sapiens