Human Gene Set: GOCC_ATP_BINDING_CASSETTE_ABC_TRANSPORTER_COMPLEX
Standard name
GOCC_ATP_BINDING_CASSETTE_ABC_TRANSPORTER_COMPLEX
Systematic name
M25836
Brief description
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter. [GOC:jl, GOC:mtg_sensu, PMID:11421269, PMID:15111107]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
