Human Gene Set: GOCC_B_WICH_COMPLEX

For the Mouse gene set with the same name, see GOCC_B_WICH_COMPLEX

Standard name GOCC_B_WICH_COMPLEX
Systematic name M43142
Brief description A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself. [GOC:bhm, PMID:16603771, PMID:21559432, PMID:23555303, PMID:26044184]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0110016
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0110016
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
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