Human Gene Set: GOCC_NADPH_OXIDASE_COMPLEX

For the Mouse gene set with the same name, see GOCC_NADPH_OXIDASE_COMPLEX

Standard name GOCC_NADPH_OXIDASE_COMPLEX
Systematic name M25833
Brief description A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires the cytosolic regulatory subunits at least NCF1/p47-phox, NCF2/p67-phox, NCF4/p40-phox and the small GTPase RAC1 or RAC2 for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2. [GOC:jl, PMID:11483596, PMID:12440767]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0043020
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0043020
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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