Human Gene Set: GOCC_PAR_POLARITY_COMPLEX


Standard name GOCC_PAR_POLARITY_COMPLEX
Systematic name M45977
Brief description A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC. [GOC:lnp, PMID:11113154, PMID:18005931, PMID:22500799, PMID:28682236]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0120157
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0120157
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references  
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NCI-60 cell lines (National Cancer Institute)
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Version history 2023.1.Hs: First Introduced.

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