Human Gene Set: GOCC_THO_COMPLEX

For the Mouse gene set with the same name, see GOCC_THO_COMPLEX

Standard name GOCC_THO_COMPLEX
Systematic name M25590
Brief description The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits. [GOC:krc, PMID:11060033, PMID:11979277, PMID:16983072]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0000347
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0000347
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2026.1.Hs: Updated to GO Release 2025-10-10.


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