Human Gene Set: GOCC_TRANSCRIPTION_FACTOR_AP_1_COMPLEX

For the Mouse gene set with the same name, see GOCC_TRANSCRIPTION_FACTOR_AP_1_COMPLEX

Standard name GOCC_TRANSCRIPTION_FACTOR_AP_1_COMPLEX
Systematic name M43121
Brief description A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes. [GOC:bf, GOC:BHF, GOC:rl, PMID:20060892, PMID:9069263, Wikipedia:AP-1_transcription_factor]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0035976
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0035976
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2026.1.Hs: Updated to GO Release 2025-10-10.


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