Human Gene Set: GOCC_VACUOLE

For the Mouse gene set with the same name, see GOCC_VACUOLE

Standard name GOCC_VACUOLE
Systematic name M5245
Brief description A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. [GOC:mtg_sensu, ISBN:0198506732]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0005773
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0005773
Filtered by similarity ? (show 2 similar ontology term(s) from the external resource)
Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references  
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GTEx compendium
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NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 911 genes
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Show members (show 912 source identifiers mapped to 911 genes)
Version history 2026.1.Hs: Updated to GO Release 2025-10-10.


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