Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer with an additional 2-C unit). This reaction is the condensation step of the endoplasmic reticulum fatty acid elongation cycle. [GOC:tb, PMID:16564093, PMID:19763486]
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C5: Ontology GO: Gene Ontology GO:MF: GO Molecular Function