Human Gene Set: GOMF_GI_O_COUPLED_SEROTONIN_RECEPTOR_ACTIVITY

For the Mouse gene set with the same name, see GOMF_GI_O_COUPLED_SEROTONIN_RECEPTOR_ACTIVITY

Standard name GOMF_GI_O_COUPLED_SEROTONIN_RECEPTOR_ACTIVITY
Systematic name M49721
Brief description Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels. [GOC:mah, PMID:18571247]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:MF: GO Molecular Function
Source publication  
Exact source GO:0001586
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0001586
Filtered by similarity ?
Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 6 genes
Gene families ? Categorize these 6 genes by gene family
Show members (show 6 source identifiers mapped to 6 genes)
Version history 2025.1.Hs: Updated to GO Release 2025-03-16.

See MSigDB license terms here. Please note that certain gene sets have special access terms.