Human Gene Set: GOMF_RAB_GERANYLGERANYLTRANSFERASE_ACTIVITY
Standard name
GOMF_RAB_GERANYLGERANYLTRANSFERASE_ACTIVITY
Systematic name
M49730
Brief description
Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family. [EC:2.5.1.60, GOC:mah, PMID:8621375]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:MF: GO Molecular Function
