Human Gene Set: GOMF_SERINE_HYDROLASE_ACTIVITY

For the Mouse gene set with the same name, see GOMF_SERINE_HYDROLASE_ACTIVITY

Standard name GOMF_SERINE_HYDROLASE_ACTIVITY
Systematic name M4452
Brief description Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). [Wikipedia:Serine_hydrolase]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:MF: GO Molecular Function
Source publication  
Exact source GO:0017171
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0017171
Filtered by similarity ? (show 2 similar ontology term(s) from the external resource)
Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 306 genes
Gene families ? Categorize these 306 genes by gene family
Show members (show 307 source identifiers mapped to 306 genes)
Version history 2025.1.Hs: Updated to GO Release 2025-03-16.

See MSigDB license terms here. Please note that certain gene sets have special access terms.