Human Gene Set: GSE13229_IMM_VS_MATURE_NKCELL_DN


Standard name GSE13229_IMM_VS_MATURE_NKCELL_DN
Systematic name M3207
Brief description Genes down-regulated in comparison of immature NK cells versus mature NK cells.
Full description or abstract Previous reports have defined three subsets of mouse NK cells on the basis of the expression of CD27 and CD11b. The developmental relationship between these subsets was unclear. To address this issue, we evaluated the overall proximity between mouse NK cell subsets defined by CD27 and CD11b expression using pangenomic gene expression profiling. The results suggest that CD27+CD11b-, CD27+CD11b+ and CD27-CD11b+ correspond to three different intermediates stages of NK cell development.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 19234143   Authors: Chiossone L,Chaix J,Fuseri N,Roth C,Vivier E,Walzer T
Exact source GSE13229_2029_200_DN
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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