Human Gene Set: GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_UP


Standard name GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_UP
Systematic name M4588
Brief description Genes up-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 5.
Full description or abstract CD25+ regulatory T cells develop in the thymus (nTregs), but may also be generated in the periphery upon stimulation of naive CD4 T cells under appropriate conditions (iTregs). The mechanisms that regulate the generation of peripheral iTregs are largely unknown. We used microarrays to gain insights into the molecular program of extrathymic Treg development.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 21347372   Authors: Prots I,Skapenko A,Lipsky PE,Schulze-Koops H
Exact source GSE24634_1438_200_UP
Related gene sets (show 31 additional gene sets from the source publication)

(show 32 gene sets from the same authors)
External links  
Filtered by similarity ?
Organism Homo sapiens
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 200 genes
Gene families ? Categorize these 200 genes by gene family
Show members (show 200 members mapped to 200 genes)
Version history 7.3: Moved to ImmuneSigDB sub-collection.

See MSigDB license terms here. Please note that certain gene sets have special access terms.