Human Gene Set: GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_DN


Standard name GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_DN
Systematic name M8576
Brief description Genes down-regulated in Th1 cells 15 days post polarization: control versus stimulated with anti-CD3 and anti-CD28.
Full description or abstract Serial comparison between Th1 and Th17 tumor-specific cells cultured in vitro and ex vivo after transferred into sublethaly irradiated B6.PL mice. Th17-derived cells acquire Th1-like properties in vivo but maintain a distinct molecular profile.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 22177921   Authors: Muranski P,Borman ZA,Kerkar SP,Klebanoff CA,Ji Y,Sanchez-Perez L,Sukumar M,Reger RN,Yu Z,Kern SJ,Roychoudhuri R,Ferreyra GA,Shen W,Durum SK,Feigenbaum L,Palmer DC,Antony PA,Chan CC,Laurence A,Danner RL,Gattinoni L,Restifo NP
Exact source GSE26030_2569_200_DN
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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