Human Gene Set: GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN


Standard name GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN
Systematic name M8464
Brief description Genes down-regulated in activated CD4 [GeneID=920] T cells: wildtype versus MIR17 [GeneID=406952] knockout.
Full description or abstract miR-17 from the miR-17-92 cluster regulate activation-induced cell death in T cells and modulate inducible regulatory T cell differentiation. We used microarrays to detail the global program of gene expression modulated by miR-17 and aim to identify the potential targets of miR-17.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 21972292   Authors: Jiang S,Li C,Olive V,Lykken E,Feng F,Sevilla J,Wan Y,He L,Li QJ
Exact source GSE32533_3153_200_DN
Related gene sets (show 5 additional gene sets from the source publication)

(show 18 gene sets from any of these authors)
External links
Filtered by similarity ?
Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 197 genes
Gene families ? Categorize these 197 genes by gene family
Show members (show 200 source identifiers mapped to 197 genes)
Version history 7.3: Moved to ImmuneSigDB sub-collection.

See MSigDB license terms here. Please note that certain gene sets have special access terms.