Human Gene Set: GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_DN


Standard name GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_DN
Systematic name M9049
Brief description Genes down-regulated in T reg: untreated ADORA2A [GeneID=135] knockout versus wildtype treated by ZM 241385 [PubChem=176407].
Full description or abstract The adenosine 2A receptor (A2AR) is expressed on regulatory T cells (Tregs), but the functional significance is currently unknown. We compared the gene expression between wild-type (WT) and A2AR knockout (KO) Tregs and between WT Tregs treated with vehicle or a selective A2AR agonist.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 22835488   Authors: Kinsey GR,Huang L,Jaworska K,Khutsishvili K,Becker DA,Ye H,Lobo PI,Okusa MD
Exact source GSE34006_3360_200_DN
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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