Human Gene Set: GSE37534_UNTREATED_VS_PIOGLITAZONE
      _TREATED_CD4_TCELL_PPARG1_AND_FOXP3
      _TRASDUCED_UP


Standard name GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP
Systematic name M8980
Brief description Genes up-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and PPARg1 form of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829].
Full description or abstract Pioglitazone treatment of CD4+FoxP3- T cells transduced with Pparg and Foxp3 up-regulated a set of genes whose products have been implicated in lipid metabolism pathways. To verify the specificity of this treatment, we performed microarray analysis on Foxp3+Pparg1-transduced CD4+FoxP3- T cells after treatment with other PPARg agonists such as Rosiglitazone (TZD) and GW1929 (non-TZD).
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 22722857   Authors: Cipolletta D,Feuerer M,Li A,Kamei N,Lee J,Shoelson SE,Benoist C,Mathis D
Exact source GSE37534_2865_200_UP
Related gene sets (show 53 additional gene sets from the source publication)

(show 280 gene sets from the same authors)
External links  
Filtered by similarity ?
Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 197 genes
Gene families ? Categorize these 197 genes by gene family
Show members (show 200 members mapped to 197 genes)
Version history 7.3: Moved to ImmuneSigDB sub-collection.

See MSigDB license terms here. Please note that certain gene sets have special access terms.