Human Gene Set: GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN


Standard name GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN
Systematic name M9272
Brief description Genes down-regulated in spleen B lymphocytes versus bone marrow plasma cells.
Full description or abstract CD138+ B220- plasma cells were sorted from bone marrow and B220+ CD23+ mature follicular B cells were sorted from the spleens. Plasma cells were sorted from C57BL/6 mice 7 days after boosting with antigen, with mice first primed with an i.p. injection of KLH/IFA followed by boost at day 21 with KLH/PBS i.p. Mature B cells were sorted from antigen-naïve C57BL/6 mice. We compared expression profiles of plasma cells and mature B cells to identify differentially expressed transcripts.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 22991471   Authors: Benson MJ,Aijö T,Chang X,Gagnon J,Pape UJ,Anantharaman V,Aravind L,Pursiheimo JP,Oberdoerffer S,Liu XS,Lahesmaa R,Lähdesmäki H,Rao A
Exact source GSE39916_3526_200_DN
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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