Human Gene Set: GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN


Standard name GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN
Systematic name M5771
Brief description Genes down-regulated in IL7R [GeneID=3575] low effector CD8 T cells versus IL7R [GeneID=3575] high effector CD8 T cells.
Full description or abstract At the peak of the CD8 T cell response to acture viral and bacterial infections, expression of the Interleukin-7 Receptor (IL-7R) marks Memory Precursor Effector CD8 T Cells (MPECs) from other Short-Lived Effector CD8 T cells (SLECs), which are IL-7Rlo. This study was designed to determine the gene expression differences between these two subsets of effector CD8 T cells.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 17723218   Authors: Joshi NS,Cui W,Chandele A,Lee HK,Urso DR,Hagman J,Gapin L,Kaech SM
Exact source GSE8678_1059_200_DN
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.


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