Human Gene Set: HALLMARK_IL6_JAK_STAT3_SIGNALING

For the Mouse gene set with the same name, see HALLMARK_IL6_JAK_STAT3_SIGNALING

Standard name HALLMARK_IL6_JAK_STAT3_SIGNALING
Systematic name M5897
Brief description Genes up-regulated by IL6 [GeneID=3569] via STAT3 [GeneID=6774], e.g., during acute phase response.
Full description or abstract  
Collection H: Hallmark
Source publication Pubmed 26771021   Authors: Liberzon A,Birger C,Thorvaldsdóttir H,Ghandi M,Mesirov JP,Tamayo P
Exact source  
Related gene sets (show 49 additional gene sets from the source publication)

(show 74 gene sets from the same authors)

(show 23 founder gene sets for this hallmark gene set)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Arthur Liberzon (MSigDB Team)
Source platform or
identifier namespace
HUMAN_GENE_SYMBOL
Dataset references (show 5 hallmark refinement datasets)

(show 2 hallmark validation datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 87 genes
Gene families ? Categorize these 87 genes by gene family
Show members (show 87 source identifiers mapped to 87 genes)
Version history 5.0: First introduced

See MSigDB license terms here. Please note that certain gene sets have special access terms.