Human Gene Set: HARRIS_HYPOXIA


Standard name HARRIS_HYPOXIA
Systematic name M10508
Brief description Genes known to be induced by hypoxia
Full description or abstract Cells undergo a variety of biological responses when placed in hypoxic conditions, including activation of signalling pathways that regulate proliferation, angiogenesis and death. Cancer cells have adapted these pathways, allowing tumours to survive and even grow under hypoxic conditions, and tumour hypoxia is associated with poor prognosis and resistance to radiation therapy. Many elements of the hypoxia-response pathway are therefore good candidates for therapeutic targeting.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 11902584   Authors: Harris AL
Exact source Box 1
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Organism Homo sapiens
Contributed by John Newman (University of Washington)
Source platform HUMAN_GENE_SYMBOL
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Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Version history 3.0: Renamed from HYPOXIA_REVIEW

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